Salk Institute for Biological Studies

Contact Info:

Elsa Molina

https://www.salk.edu/science/core-facilities/omics/

Grants and Identifiers:

RRID: RRID:SCR_026396

Instrumentation:

Services Provided:

Relevant Publications:

1.) Popay TM, Pant A, Munting F, Tastemel M, Black ME, Haghani N, Dixon JR (2026 Feb 16). Acute NIPBL depletion reveals in vivo dynamics of loop extrusion and its role in transcription activation. Nature genetics, (), . . PMCID: 13019969.

2.) Saia Cereda VAM, Sharma A, Flanagan K, Elmsaouri S, Steiner S, Benassi S, Reis-de-Oliveira G, Whiteley JT, Chandrabhatta A, Mendes APD, Randolph-Moore L, Xenitopoulos D, Jetzer M, Oefner R, Benner C, Santos R, Yeo GW, Marchetto MC (2025 Oct 8). Human AUTS2 regulates neurodevelopmental pathways via dual DNA/RNA binding. bioRxiv : the preprint server for biology, (), . . PMID: 41278797.

3.) Sturmlechner I, Jain A, Hu B, Jadhav RR, Cao W, Okuyama H, Tian L, Weyand CM, Goronzy JJ (2025 Jul 10). Antigen specificity shapes distinct aging trajectories of memory CD8⁺ T cells. Nature communications, 16(1), 6394. . PMID: 40640147.

4.) Banerjee P, Wang Y, Carnevale LN, Patel P, Raspur CK, Tran N, Zhang X, Natarajan R, Roberts AJ, Baran PS, Lipton SA (2025 Feb 28). diAcCA, a Pro-Drug for Carnosic Acid That Activates the Nrf2 Transcriptional Pathway, Shows Efficacy in the 5xFAD Transgenic Mouse Model of Alzheimer’s Disease Antioxidants, 14(3), 293. . PMCID: 11939361.

Description:

Core offers single-cell and spatial omics services. Provides consultation, expert guidance in experimental design, and technologies tailored for innovative research in genomics. Facility is equipped with 10x Genomics Chromium X and Xenium systems, Vizgen MERSCOPE, Bruker/NanoString GeoMx Digital Spatial Profiler, and nCounter MAX.