Beckman Coulter CytoFLEX Flow Cytometer

Flow Cytometer provides performance needed for sensitivity and resolution throughout all configurations. [Product Link]

RRID:SCR_019627

cite this instrument

Beckman Coulter CytoFLEX SRT Cell Sorter

Offers multiple configurations with the option to easily upgrade. Instrument can be configured to use up to four lasers and up to 15-color detection to identify subtle differences between cells. Core Facility’s CytoFLEX SRT is four-laser platform (405, 488, 561 and 638nm) instrument capable of detecting FSC, SSC and 15-colors and is able to sort up to four separate populations from the same sample, and deposit them in variety of tubes and plates. Operates under CytExpert SRT Software. [Product Link]

RRID:SCR_025068

cite this instrument

Cytek Aurora Spectral Analyzer

Prodigy incorporating a combination of patent-pending technologies that takes flow cytometry to the next level of performance and flexibility. With up to five lasers, three scattering channels, and 64 fluorescence channels, the Aurora suits every laboratory's needs, from to high complexity applications. A paradigm shifting optical design provides unprecedented flexibility, enabling the use of a wide array of new fluorochrome combinations without reconfiguring your system for each application. The state-of-the-art optics and low-noise electronics provide excellent sensitivity and resolution. Flat-top beam profiles, combined with a ly designed fluidics system, translate to outstanding performance at high sample flow rates. [Product Link]

RRID:SCR_019826

cite this instrument

Beckman Coulter CytoFLEX Nano

Specifically designed for the analysis of nanoparticles, the CytoFLEX nano Flow Cytometer overcomes the limitations of traditional flow cytometry, giving researchers a sensitive, consistent and flexible solution that can help them advance their research. The CytoFLEX nano Flow Cytometer is a pivotal development in flow cytometry that allows users to analyze extracellular vesicles (EVs) at least as small as 40 nm* with ease while simultaneously offering up to 6 separate fluorescent channels of detection and 5 side scatter channels, to deliver full characterization and open additional avenues for your nanoparticle research.

Beckman Coulter CytoFLEX SRT

CytoFLEX SRT Cell Sorter is a benchtop sorter. It is capable of meeting requirements for a wide range of sorting needs. And like the CytoFLEX Platform, it includes innovative technologies that simplify the setup and operation, empowering investigators to focus on the research questions. The Violet-Blue-Yellow Green-Red (V-B-Y-R) Series has 15 fluorescent detectors when fully activated. It can be purchased with as few as five with an option to activate additional lasers and detectors with an activation key. It is capable of complex sort logic with different combinations of sort settings on each of four streams, including the ability to catch aborts of one of the other streams. An optional Biosafety Cabinet including aerosol evacuation or a standalone Aerosol Evacuation Unit is available. Capable of complex sort logic, including 4-way sorting, Mixed Mode sorting, and the ability to catch aborts and preserve precious cells Setup is smart and simplified, using automation to establish and maintain the sort stream Remote support ready using BeckmanConnect for on demand access to our technical specialists, perform many routine maintenance procedures independently Explore more resources about the CytoFLEX SRT benchtop sorter here.

Becton Dickinson FACSAria Symphony S6

The BD FACSymphony™ S6 System adds cutting-edge technology to the performance of the BD FACSAria™ Fusion Cell Sorter and the innovative optics of the BD FACSymphony™ A5 Cell Analyzer to power your scientific discovery. Configurable up to 50 parameters to define phenotypically distinct subpopulations and isolate populations previously only available for analysis Flexibility to sort subpopulations up to 6 ways or into plates or slides

ONi Aploscope/Aploflow

Super resolution SMLM with 15nm resolution. Capable of single molecule tracking, live cell imaging, protein interactions, and dSTORM/PALM. Contains automated fluidics system and sample prep.

Revvity Celigo

Celigo is a plate-based benchtop brightfield and fluorescent imaging system designed for whole-well live-cell analysis and cell sample characterization. The Celigo system images and analyzes cells in various types of vessels including 6 – 1536 well plates, T25, T75 flasks, 10 cm dishes, and glass slides without disturbing their natural state. Individual cell level analysis is easily generated, providing cell level insights unlike ELISA or protein-based assays, and at a faster rate than flow cytometry.

SPARTA Biodiscovery AGIS1

Label-free single particle optical tweezer trapping with Raman Spectroscopy analysis for chemical composition and dynamic reaction monitoring. Allows for chemical formulations of LNPs for production.

Spectradyne ARC

Microfluidic pulse sensing in a non-optical fluorescent array. Size and concentration via non-laser driven pulse resistance voltage measurements.

Unchained Labs Leprechaun

Interferometer and immunofluorescence for titer, structure, RNA content, and contaminant analysis of Lentivirus, viral vectors, and exosomes.

Unchained Labs STUNNER

UV/Vis and dynamic light scattering for LNP sizing and polydispersity, concentration, aggregation, and RNA quantification. Nanovesicle protein quantification and conjugate characterization. Viral vector capsid titers and content ratios.

Zeiss LSM 900 with Axiovert and Airyscan 2

Confocal microscope with Airyscan 2 and Dynamics profiler for resolution of 90nm with Fluorescent Correlation Spectroscopy to understand population dynamics and molecular concentration. Allows for FRET and FRAP for greater dye pairings and cellular interactions.

Citation IDs: RRID:SCR_022263

cite this instrument