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Montana State University - Animal Resources Center

Montana State University

Contact Info:

Kerri Jones

100 ARC Building Tietz Hall

Montana State University

Bozeman, MT 59717

https://www.montana.edu/animalresources/

Grants and Identifiers:

RRID: RRID:SCR_026351

Instrumentation:

Services Provided:

BSL 1 And 2 Procedure Rooms

Lab Animal Care

Lab Animal Housing

Relevant Publications:

1.) Brown K, Vahidi G, Hislop BD, Moody M, Watson S, Welhaven HD, Behzad R, Paton KO, Karim L, June RK, Martin SA, Heveran CM (2025 Jun 3). Short-term high-fat diet impacts bone material properties and metabolism for adult and aged C57BL/6JN mice. Communications biology, 8(1), 850. . ID: 40461602.


2.) Luu AM, Hatton AA, Gattiker J, Shepardson KM, Hall MN, Benson E, Bimczok D, Rynda-Apple A (2025 May 28). TLR2 or TLR4 stimulation induces transmembrane (tm)TNF-driven priming in macrophages which results in improved clearance of a subsequent Staphylococcus aureus infection. Journal of innate immunity, (), 1-28. doi: 10.1159/000546011. ID: 40435995.


3.) North RJ, Cooper G, Mears L, Bothner B, Dlakić M, Merzdorf CS (2025 May 19). Persistent Transcriptome Alterations in Zebrafish Embryos After Discontinued Opioid Exposure. International journal of molecular sciences, 26(10), . . ID: 40429979.


4.) Wolfe TM, Jo J, Pinkham NV, Garey KW, Walk ST (2025 Apr 2). The impact of ibezapolstat and other Clostridioides difficile infection-relevant antibiotics on the microbiome of humanized mice. Antimicrobial agents and chemotherapy, 69(4), e0160424. . ID: 39998294.


5.) Welhaven HD, Welfley AH, Brahmachary PP, Smith DF, Bothner B, June RK (2025 Feb 7). Tissue-specific and spatially dependent metabolic signatures perturbed by injury in skeletally mature male and female mice. bioRxiv : the preprint server for biology, (), . . ID: 39975211.


6.) Falvo CA, Crowley DE, Benson E, Hall MN, Schwarz B, Bohrnsen E, Ruiz-Aravena M, Hebner M, Ma W, Schountz T, Rynda-Apple A, Plowright RK (2025 Feb). Diet-induced changes in metabolism influence immune response and viral shedding in Jamaican fruit bats. Proceedings. Biological sciences, 292(2041), 20242482. . ID: 39968620.


7.) Cooper G, North R, Hunt-Smith T, Larson J, Rennie M, Bailey ML, Scarlata S, Merzdorf CS, Bothner B (2025 Jan 26). Persistent Metabolic Changes Are Induced by 24 h Low-Dose Lead (Pb) Exposure in Zebrafish Embryos. International journal of molecular sciences, 26(3), . . ID: 39940818.


8.) Miettinen HM, Abbott MJ, Evans AB (2025). A mix-and-match reverse genetics system for evaluating genetic determinants of orthobunyavirus neurological disease. PloS one, 20(4), e0315694. . ID: 40294121.


9.) Dauenhauer LA, Hislop BD, Brahmachary P, Devine C, Gibbs D, June RK, Heveran CM (2024 Nov). Aging alters the subchondral bone response 7 days after noninvasive traumatic joint injury in C57BL/6JN mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 42(11), 2450-2460. doi: 10.1002/jor.25921. ID: 38923623.


10.) Pincus SH, Cole FM, Ober K, Tokmina-Lukaszewska M, Marcotte T, Kovacs EW, Zhu T, Khasanov A, Copié V, Peters T (2024 Oct 22). Conjugation of anti-HIV gp41 monoclonal antibody to a drug capable of targeting resting lymphocytes produces an effective cytotoxic anti-HIV immunoconjugate. Journal of virology, 98(10), e0064724. . ID: 39283123.


11.) Rynda-Apple A, Reyes Servin J, Lenz J, Roemer J, Benson EE, Hall MN, Shepardson KM (2024 Oct 15). IFN Receptor 2 Regulates TNF-α-Mediated Damaging Inflammation during Aspergillus Pulmonary Infection. Journal of immunology (Baltimore, Md. : 1950), 213(8), 1202-1211. . ID: 39212415.


12.) Luu AM, Shepardson KM, Rynda-Apple A (2024 Oct). A Comprehensive Protocol for the Collection, Differentiation, Cryopreservation, and Resuscitation of Primary Murine Bone Marrow Derived Macrophages (BMDM). Immunological investigations, 53(7), 1001-1012. . ID: 39115808.


13.) Blackwell KH, Walk HMG, Peters LR, Gunlikson EM, Bright JC, Kominsky DJ, Walk ST (2024 Sep 20). A simplified protocol for deriving sterile, infectious murine Heligmosomoides polygyrus bakeri larvae. STAR protocols, 5(3), 103144. . ID: 39167493.


14.) Vahidi G, Boone C, Hoffman F, Heveran C (2024 Sep). Aging decreases osteocyte peri-lacunar-canalicular system turnover in female C57BL/6JN mice. Bone, 186(), 117163. . ID: 38857854.


15.) Crowley DE, Falvo CA, Benson E, Hedges J, Jutila M, Ezzatpour S, Aguilar HC, Ruiz-Aravena M, Ma W, Schountz T, Rynda-Apple A, Plowright RK (2024 Sep). Bats generate lower affinity but higher diversity antibody responses than those of mice, but pathogen-binding capacity increases if protein is restricted in their diet. PLoS biology, 22(9), e3002800. . ID: 39316608.


16.) Costello SM, Schultz A, Smith D, Horan D, Chaverra M, Tripet B, George L, Bothner B, Lefcort F, Copié V (2024 Jul 31). Metabolic Deficits in the Retina of a Familial Dysautonomia Mouse Model. Metabolites, 14(8), . . ID: 39195519.


17.) Domanico LF, Dunn GP, Kobiler O, Taylor MP (2024 May 14). A dual fluorescent herpes simplex virus type 1 recombinant reveals divergent outcomes of neuronal infection. Journal of virology, 98(5), e0003224. . ID: 38651900.


18.) Fredrikson JP, Domanico LF, Pratt SL, Loveday EK, Taylor MP, Chang CB (2024 Mar). Single-cell herpes simplex virus type 1 infection of neurons using drop-based microfluidics reveals heterogeneous replication kinetics. Science advances, 10(9), eadk9185. . ID: 38416818.


19.) Devine CC, Brown KC, Paton KO, Heveran CM, Martin SA (2024 Feb). Rapamycin does not alter bone microarchitecture or material properties quality in young-adult and aged female C57BL/6 mice. JBMR plus, 8(2), ziae001. . ID: 38505525.


20.) Vahidi G, Moody M, Welhaven HD, Davidson L, Rezaee T, Behzad R, Karim L, Roggenbeck BA, Walk ST, Martin SA, June RK, Heveran CM (2023 Aug). Germ-Free C57BL/6 Mice Have Increased Bone Mass and Altered Matrix Properties but Not Decreased Bone Fracture Resistance. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 38(8), 1154-1174. . ID: 37221143.


21.) Cheney AM, Costello SM, Pinkham NV, Waldum A, Broadaway SC, Cotrina-Vidal M, Mergy M, Tripet B, Kominsky DJ, Grifka-Walk HM, Kaufmann H, Norcliffe-Kaufmann L, Peach JT, Bothner B, Lefcort F, Copié V, Walk ST (2023 Jan 13). Gut microbiome dysbiosis drives metabolic dysfunction in Familial dysautonomia. Nature communications, 14(1), 218. . ID: 36639365.


22.) Hislop BD, Devine C, June RK, Heveran CM (2022 Dec). Subchondral bone structure and synovial fluid metabolism are altered in injured and contralateral limbs 7 days after non-invasive joint injury in skeletally-mature C57BL/6 mice. Osteoarthritis and cartilage, 30(12), 1593-1605. . ID: 36184957.


23.) Welhaven HD, Vahidi G, Walk ST, Bothner B, Martin SA, Heveran CM, June RK (2022 Jul). The Cortical Bone Metabolome of C57BL/6J Mice Is Sexually Dimorphic. JBMR plus, 6(7), e10654. . ID: 35866150.


24.) Roggenbeck BA, Bull Chief LK, Walk ST (2021 May 30). Antibiotic perturbation of the murine gut microbiome introduces inter-individual susceptibility to arsenic. Toxicology, 456(), 152798. . ID: 33901602.


25.) Coe GL, Pinkham NV, Celis AI, Johnson C, DuBois JL, Walk ST (2021 Jan 15). Dynamic Gut Microbiome Changes in Response to Low-Iron Challenge. Applied and environmental microbiology, 87(3), . . ID: 33188000.


Description:

The Animal Resources Center (ARC) is an AAALAC approved animal research facility, providing researchers with the opportunity to study a diverse number of animal species. ARC maintains animal housing rooms, observation rooms, and procedure rooms at BSL 1 and 2 containment levels. The ARC is supported by certified veterinarians and animal care technicians who provide technical support and veterinary care.