Dartmouth Cancer Center
Radu V Stan
1 Medical Center Drive
Lebanon, NH 03756
https://cancer.dartmouth.edu/scientists-researchers/irradiation-imaging-microscopy-animal-resource
RRID: RRID:SCR_025077
Other Citation Identifiers 5P30CA023108
Agilent/BioTek Cytation 5 imager with BioSpa 8 incubator
live cell high ththroughput imager for phase contrast and fluorescence
Akoya Vectra 3 automated slide scanning system
fluorescence and brightfield automated slide scanner with multispectral acquisition and spectral unmixing
Alveole Primo bioengineering system
UV light based micropatterning and microfabrication system
FEI Vitrobot
grid freezing for cryoEM
GE eXplore Locus In-vivo scanner
In-vivo CT imaging
GE eXplore Micro CT scanners
In-vitro/ex-vivo CT imaging
Leica ACE600 Coating system
high vacuum metal and carbon coater
Leica Ultracut-6
ultramicrotome
Leica Ultracut-7
ultramicrotome
Phillips Mosaic
micro-PET scanner
Precision X-Irradiation X-RAD320
Irradiator for cells and whole animals, diagnostic x-ray and bioluminescence
Siemens Somotom
CT scanner
ThermoFisher Helios CX5 SEM
FIB-SEM with STEM3+ detector and cryomat
ThermoFisher Talos F200i TEM and STEM
TEM ande STEM microscope
Toussimis 950
critical point dryer
Varian Trilogy / TrueBeam 6-18 MeV accelerator
6-18 MeV accelerator
Varian/Brucker Direct-Drive 9.4T
9.4T MR imager for small animals
Visual Sonics Vevo
ulrasound
Xenogen Spectrum CT
IVIS and CT in vivo imager
Zeiss LSM 800 with Airyscan Confocal Laser Scanning Microscope
Confocal Laser Scanning Microscope with Airyscan
2D & 3D Illustration
3D & 4D Image Processing Stations
Acoustic Angiography
Analysis Workstations
Bioluminsecence Imaging
Brightfield Microscope With Axial Sectioning Capability
Brightfield Microscopy
Cell Imaging
Clinical Imaging - Small Animal (luminescence/fluorescence)
Clinical Imaging - Small Animal (X-ray, Ultrasound, microCAT, MRI)
Collaborative Cross Mice
Colony Management
Confocal Microscopy
Confocal/ Super Resolution Microscope
Crossing
Cryo Light Microscopy
Cryo-Electron Microscopy
Cryo-Electron Microscopy Of Vitrified Sections (CEMOVIS)
Cryo-Scanning Electron Microscopy
Differential Interference Contrast Microscopy
EDX
Electron Microscopy
Fabrication
Fluorescence Microscope With Optical Sectioning Capability
Focused Ion Beam (FIB)
Germfree Mice
High-plex Immunofluorescence
Image Aquisition
Image Processing And Analysis
Incucyte
Irradiation
Laser Scanning
Live Cell Imaging
MicroCT
MicroED
Microscopy
Microstructure Characterization
Microtomy/Electron
Molecular Imaging
Multiplex Fluorescence
Multiplexed Immunofluorescence
Optical Spectroscopy
Phase Contrast Microscopy
Phenotyping
Rodent Study
Scanning 20X Brightfield
Scanning 20X Flourescent
Scanning 20X Fluorescent
Scanning 40X Brightfield
Scanning 40X Fluorescent
Scanning Electron Microscopy
Slide Scanning
Stereomicroscopy
Super-resolution Microscopy
Transmission Electron Microscopy
Widefield Microscopy
Xenograft / Xenotransplantation
1.) Graber DJ, Sentman ML, Cook WJ, Sentman CL (2026 Mar 5). 5xFAD-NSG mice: a preclinical Alzheimer model for human cell therapy studies. bioRxiv : the preprint server for biology, (), . . PMCID: 13001429.
2.) Ubert CS, Petryakov SV, Kmiec MM, Daniel NJ, Kheirollah A, O'Connell RC, Kassey VB, Hoopes PJ, Kuppusamy P (2026 Mar). A Flexible RF Coil Design (OxyTrack) for Oxygen Measurements in Body Cavities. Magnetic resonance in medicine, 95(3), 1879-1889. doi: 10.1002/mrm.70180. PMID: 41240324.
3.) García HA, Nguyen HM, Kwon CY, Streeter SS, Torres VC, Nguyen MH, LaRochelle EPM, Ruiz AJ, Henderson E, Davis SC, Samkoe KS (2026 Feb). Evaluation of analytical models to estimate depth of fluorescence objects in biological media. Journal of Biomedical Optics, 31(2), . . PMCID: 12926504.
4.) Kamerkar SC, Kang T, Stan RV, Usherwood EJ, Higgs HN (2025 Nov 12). The tumor suppressor LACTB remodels mitochondria to promote cytochrome c release and apoptosis Science Advances, 11(46), eadx7809. . PMCID: 12609066.
5.) Demidov VV, Jackson OP, Demidova N, Gunn JR, Gitajn IL, Elliott JT (2025 Sep 23). Integrating optical coherence tomography and bioluminescence with predictive modeling for quantitative assessment of methicillin-resistant S. aureus biofilms Journal of Biomedical Optics, 30(), S34111. . PMCID: 12456866.
6.) Demidova N, Gunn JR, Gitajn IL, Alex Vitkin I, Thomas Elliott J, Demidov VV (2025 Apr 1). Optical coherence tomography for label-free detection and characterization of methicillin-resistant S. aureus biofilms Journal of Biomedical Optics, 30(4), 046003. . PMCID: 11960790.
7.) (). PMCID: 12997104.
The Irradiation, Imaging, Microscopy and Animal Cancer Models Shared Resource at Dartmouth Cancer center is an integrated resource offering services in Irradiation, pre-clinical imaging of small and large animals, light and electron microscopy as well as large and small animal cancer models.
The Irradiation Section assists investigators in radiation treatment planning and delivery of ionizing irradiation to cells, rodents and large animals with engineered, transplanted or spontaneous tumors.
The Imaging Section provides technologies for non-invasive, whole-animal imaging of animals used in preclinical research studies.
The Microscopy Section provides access to point scanning confocal microscopy with Airyscan super resolution, conventional bright field and fluorescence light microscopy, high throughput live imaging, automated slide scanning and image analysis resources. The electron microscopy resource provides state of the art scanning , transmission and scanning transmission electron microscopy.
The Animal Cancer Models section supports the generation and utilization of large and small animals for modeling cancer and other human diseases. The section has expertise in generating cancer models using wild type or genetically engineered animals in immunocompetent and immunocompromised backgrounds, as well as mice with a humanized immune system.
