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Stanford Functional Genomics Facility

Stanford Medicine

Contact Info:

John Coller

269 Campus Dr

CCSR 0120

Stanford, CA 94305-5177

https://med.stanford.edu/sfgf.html

Grants and Identifiers:

RRID: RRID:SCR_002050

Instrumentation:

Services Provided:

Assays and Measurements

Computational - Bioinformatics

Copy Number Variation (CNV)

Cytogenetics

Data Analysis

DNA Analysis

Genomics

Genotyping

Library Services

Microarray

Molecular Library Services

Nucleic Acid Extraction

Optical Imaging

PCR Arrays

Phosphor Imaging

Proteomics

Real-time qPCR

RNA analysis

RNA Integrity

Sequencing - Capillary Sequencing

Sequencing - DNA Sequencing

Sequencing - Next Generation Sequencing (NGS)

Shared Instrumentation Oversight & Maintenance

Western Blot

Relevant Publications:

1.) Pham THM, Xue Y, Brewer SM, Bernstein KE, Quake SR, Monack DM (2023 Jan 6). Single-cell profiling identifies ACE(+) granuloma macrophages as a nonpermissive niche for intracellular bacteria during persistent Salmonella infection. Science advances, 9(1), eadd4333. . PMID: 36608122.


2.) Hu J, Boeri M, Sozzi G, Liu D, Marchianò A, Roz L, Pelosi G, Gatter K, Pastorino U, Pezzella F (2015 Aug). Gene Signatures Stratify Computed Tomography Screening Detected Lung Cancer in High-Risk Populations. EBioMedicine, 2(8), 831-40. . PMID: 26425689.


3.) Xie H, Zhao Y, Caramuta S, Larsson C, Lui WO (2012). miR-205 expression promotes cell proliferation and migration of human cervical cancer cells. PloS one, 7(10), e46990. . PMID: 23056551.


4.) Liu D, Hu J, Agorreta J, Cesario A, Zhang Y, Harris AL, Gatter K, Pezzella F (2010 Oct 28). Tumor necrosis factor receptor-associated protein 1(TRAP1) regulates genes involved in cell cycle and metastases. Cancer letters, 296(2), 194-205. doi: 10.1016/j.canlet.2010.04.017. PMID: 20471161.


5.) Granjon A, Gustin MP, Rieusset J, Lefai E, Meugnier E, Güller I, Cerutti C, Paultre C, Disse E, Rabasa-Lhoret R, Laville M, Vidal H, Rome S (2009 Nov). The microRNA signature in response to insulin reveals its implication in the transcriptional action of insulin in human skeletal muscle and the role of a sterol regulatory element-binding protein-1c/myocyte enhancer factor 2C pathway. Diabetes, 58(11), 2555-64. . PMID: 19720801.


6.) van Baarsen LG, Vosslamber S, Tijssen M, Baggen JM, van der Voort LF, Killestein J, van der Pouw Kraan TC, Polman CH, Verweij CL (2008 Apr 2). Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients. PloS one, 3(4), e1927. . PMID: 18382694.


7.) Higgins JP, Kaygusuz G, Wang L, Montgomery K, Mason V, Zhu SX, Marinelli RJ, Presti JC Jr, van de Rijn M, Brooks JD (2007 May). Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray. The American journal of surgical pathology, 31(5), 673-80. . PMID: 17460449.


8.) Chan DA, Krieg AJ, Turcotte S, Giaccia AJ (2007). HIF gene expression in cancer therapy. Methods in enzymology, 435(), 323-45. . PMID: 17998061.


9.) Ekelund E, Saaf A, Tengvall-Linder M, Melen E, Link J, Barker J, Reynolds NJ, Meggitt SJ, Kere J, Wahlgren CF, Pershagen G, Wickman M, Nordenskjold M, Kockum I, Bradley M (2006 Jun). Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis. American journal of human genetics, 78(6), 1060-5. . PMID: 16685656.


Description:

The Stanford Functional Genomics Facility (SFGF) provides high-throughput sequencing (Illumina HiSeq 4000, NextSeq 500, MiSeq and MiniSeq), microarray gene expression and genotyping services (Affymetrix, Agilent and Illumina) to the Stanford research community and outside institutions. The facility also provides 24/7 access to instruments, equipment and software utilized within the genomics field.