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UC Davis Molecular Pharmacology and Chemical Biology Shared Resource

University of California, Davis

Contact Info:

Aiming Yu

Aggie Square, Room 4652

4480 2nd Ave

Sacramento, CA 95817

https://health.ucdavis.edu/cancer/research/sharedresources/mpcb

Grants and Identifiers:

RRID: RRID:SCR_023584

Instrumentation:

Automated peptide synthesizers

Confocal microscope

Four HIPA- compliant, ultra-low freezers storing up to 72,000 aliquots per freezer

FPLC systems

Lago X in vivo animal imaging system

LC-MS/MS and HPLC systems

Lyophilizers

Seahorse and IncuCyte live-cell analyzers

Services Provided:

Chemical Biology Studies

Clinical Specimens And PK/PD Studies

Preclinical Molecular Pharmacology Studies

Relevant Publications:

Description:

The Molecular Pharmacology and Chemical Biology Shared Resource (MPCBSR) provides essential and a broad spectrum of services for the assessment of new therapeutics, including high-quality collection and management of clinical trial specimens and determination of clinical PK/PD and potential drug-drug interactions (DDI), pharmacological studies on novel therapeutics in preclinical models, including DM/PK/PD, on-target mechanisms, biomarkers, and combination effects, and chemical synthesis of new compounds and drug delivery nanomaterials for improved therapy. The Molecular Pharmacology and Chemical Biology Shared Resource is part of UC Davis Health Comprehensive Cancer Center.