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Emory Glycomics and Molecular Interactions Core (EGMIC)

Emory University

Contact Info:

Yi Lasanajak, MS,MPH Tehcnical Director

615 Michael Street, Room 665A

Atlanta, GA 30322

https://www.cores.emory.edu/egmic/

Grants and Identifiers:

RRID: RRID:SCR_023524

Instrumentation:

Services Provided:

Relevant Publications:

1.) Lin B, Woo S, Philbrick A, Bacsa J, Laskey E, Mehra N, Gondil VS, Mei JA, Jones G, Pavelka MS, Dziejman M, Shutter DA, Melander C, Perritt AM, Jakober R, Shen Y, Chang W-C, Quave CL, Dunman PM, Luedemann G (2025 Oct 29). Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments. mSphere, 10(10), e0036725. . PMID: 40985724.


2.) Zhang Q, Azzam T, Lasanajak Y, Sundberg EJ, Song X (2025 Jun 6). Oxidative Release of Natural Glycans (ORNG): Preparation of Truncated N-glycans for Engineering Glycoproteins. Chemistry (Weinheim an der Bergstrasse, Germany), 31(32), e202501020. doi: 10.1002/chem.202501020. PMID: 40273031.


3.) Zhang Q, Lasanajak Y, Yan M, Chen G, Song X (2025 Apr 4). Streamlined gram-scale natural N-glycan production using reversible tagging after oxidative release of natural glycans. Communications chemistry, 8(1), 103. . PMID: 40185879.


4.) Zhang H, Bhakta D, Saha A, Peddireddy SP, Bao S, Li L, Handali S, Secor WE, Fraga LA, Fairley JK, Sarkar A (2025 Apr 1). Sample-sparing multiplexed antibody Fc biomarker discovery using a reconfigurable integrated microfluidic platform Lab on a Chip, (), . . PMCID: 12060099.


5.) Zhang Q, Lasanajak Y, Song X (2024 Oct 22). Oxidative Release of Natural Glycans: Unraveling the Mechanism for Rapid N-Glycan Glycomics Analysis. Analytical chemistry, 96(42), 16750-16757. . PMID: 39387489.


Description:

The mission of Emory Glycomics and Molecular Interactions Core (EGMIC) is to provide investigators in the Emory community access to methods and technology being used and currently under development in the rapidly developing area of glycomics and molecular interactions. We will accomplish this through individual consultation with investigators, who find a need to address questions regarding glycosylation, the most common posttranslational modification, and protein-glycan interactions. We use leading mass spectrometry and glycan microarray technologies to help understand the functions of glycans and glycan binding proteins. Our priority is to serve the needs of investigators at Emory University, but we are also capable of providing service to investigators at other institutions.