University of Arizona
Douglas Cromey
1333 N Martin Ave
Tucson, AZ 85721
https://www.cores.arizona.edu/facilities/opticalimaging/
RRID: RRID:SCR_023355
Confocal Microscopy
Confocal/ Super Resolution Microscope
Fluorescence Microscope With Optical Sectioning Capability
Image Aquisition
Image Processing And Analysis
Microscopy
Multiphoton Microscopy
Multiphoton/ Harmonic Generation Microscope
Stereomicroscopy
Super-resolution Microscopy
Widefield Microscopy
1.) Agarwal V, Pham H, Bartko SG, Taylor MT (2025 Nov 3). Cation-Cation Photosensitization for Protein Ligation and Intracellular Catalysis bioRxiv, (), 2025.11.03.686045. . PMCID: 12637585.
2.) Bjork RT, Patel FZ, Daly MS, Miller JE (2025 Sep 13). Evaluating alpha-synuclein proteinopathy and consequences for birdsong in zebra finch basal ganglia area X. Behavioural brain research, 493(), 115698. . PMID: 40505974.
3.) Frisbey AA, Nash TE, Goshe MB, Clouse SD, Frost CJ, Tax FE (2025 Jul). CEPR1 regulates Arabidopsis thaliana root architecture by modulating auxin production via NIT1. The Plant journal : for cell and molecular biology, 123(2), e70331. doi: 10.1111/tpj.70331. PMID: 40664202.
4.) Jiang Y, Wang Z, Li W, Ma T, Li M, Wu S, Lin E, Flader KE, Ma M, Chang M, Li H, Wang W, Lu J (2025 Jun 15). Enhanced delivery of camptothecin to colorectal carcinoma using a tumor-penetrating peptide targeting p32. Acta biomaterialia, 200(), 629-640. . PMID: 40379119.
5.) McDermott KE, Barnes CA (2025 Jun). An immunohistochemical protocol for visualizing adrenergic receptor subtypes in the rhesus macaque hippocampus. Journal of neuroscience methods, 418(), 110410. . PMID: 40024458.
6.) Jiang Y, Wang Z, Li W, Ma T, Li M, Wu S, Lin E, Flader KE, Ma M, Chang M, Li H, Wang W, Lu J (2025 May 14). Improving Camptothesome Delivery to Colorectal Carcinoma with a Tumor-Penetrating Peptide Targeting p32 Acta biomaterialia, 200(), 629-640. . PMCID: 12182993.
7.) Gupta AK, Minocha E, Koss KM, Naved BA, Safar-Boueri L, Wertheim JA, Gallon L (2025 May). A kidney organoid-based readout to assess disease activity in primary and recurrent focal segmental glomerulosclerosis. Kidney international, 107(5), 888-902. doi: 10.1016/j.kint.2025.01.018. PMID: 39914654.
8.) Escoto A, Hecksel R, Parkinson C, Crane S, Atwell B, King S, Ortiz Chavez D, Jannuzi A, Sands B, Bitler BG, Fehniger TA, Paek AL, Padi M, Schroeder J (2025 Feb). Nuclear EGFR in breast cancer suppresses NK cell recruitment and cytotoxicity. Oncogene, 44(5), 288-295. doi: 10.1038/s41388-024-03211-0. PMID: 39521886.
9.) Hostler AC, Hahn WW, Hu MS, Rennert R, Fischer KS, Barrera JA, Duscher D, Januszyk M, Henn D, Sivaraj D, Yasmeh JP, Kussie HC, Granoski MB, Padmanabhan J, Vial IN, Riegler J, Wu JC, Longaker MT, Chen K, Maan ZN, Gurtner GC (2024 Dec 13). Endothelial-specific CXCL12 regulates neovascularization during tissue repair and tumor progression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 38(24), e70210. doi: 10.1096/fj.202401307R. PMID: 39698751.
10.) Bernard K, Mota JA, Wene P, Corenblum MJ, Saez JL, Bartlett MJ, Heien ML, Doyle KP, Polt R, Hay M, Madhavan L, Falk T (2024 Nov). The angiotensin (1-7) glycopeptide PNA5 improves cognition in a chronic progressive mouse model of Parkinson's disease through modulation of neuroinflammation. Experimental neurology, 381(), 114926. doi: 10.1016/j.expneurol.2024.114926. PMID: 39153685.
11.) MacIsaac AR, Wellington AJ, Filicetti K, Eggers ED (2024 Oct). Impaired dopamine signaling in early diabetic retina: Insights from D1R and D4R agonist effects on whole retina responses. Experimental eye research, 247(), 110049. . PMID: 39151774.
12.) MacIsaac AR, Wellington AJ, Filicetti K, Eggers ED (2024 Aug 14). Impaired Dopamine Signaling in Early Diabetic Retina: Insights from D1R and D4R Agonist Effects on Whole Retina Responses Experimental eye research, 247(), 110049. . PMCID: 11392630.
13.) Hoyer-Kimura C, Hay M, Konhilas JP, Morrison HW, Methajit M, Strom J, Polt R, Salcedo V, Fricks JP, Kalya A, Pires PW (2024 Aug 1). PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia Aging and Disease, 15(4), 1927-1951. . PMCID: 11272189.
14.) Sinakevitch IT, McDermott KE, Gray DT, Barnes CA (2024 Jul 29). A combined MRI, histological and immunohistochemical rendering of the rhesus macaque locus coeruleus (LC) enables the differentiation of three distinct LC subcompartments Journal of chemical neuroanatomy, 140(), 102449. . PMCID: 11392618.
15.) Seka DJ, Schulz AK, Thaker TM, Tomasiak TM (2024 May 22). The N-terminal signature motif on the transporter MCT1 is critical for CD147-mediated trafficking The Journal of Biological Chemistry, 300(6), 107333. . PMCID: 11176948.
16.) Lemke MD, Abate AN, Woodson JD (2024 May 3). Investigating the mechanism of chloroplast singlet oxygen signaling in the Arabidopsis thaliana accelerated cell death 2 mutant Plant Signaling & Behavior, 19(1), 2347783. . PMCID: 11073415.
17.) Thota LNR, Lopez Rosales JE, Placencia I, Zemskov EA, Tonino P, Michael AN, Black SM, Chignalia AZ (2023 Sep 26). The Pulmonary Endothelial Glycocalyx Modifications in Glypican 1 Knockout Mice Do Not Affect Lung Endothelial Function in Physiological Conditions. International journal of molecular sciences, 24(19), . . PMID: 37834029.
18.) Lemke MD, Woodson JD (2023). A genetic screen for dominant chloroplast reactive oxygen species signaling mutants reveals life stage-specific singlet oxygen signaling networks. Frontiers in plant science, 14(), 1331346. . PMID: 38273946.
The Office of Research and Partnerships (ORP) Imaging Cores - Optical facility is a scientific core facility with two locations (Marley, Life Sciences North) dedicated to the acquisition of images for research, industrial and clinical applications. We offer multi-user access to high quality state-of-the-art technologies and cost-effective analytical services.
The Marley location features an inverted point scanning confocal microscope, an upright confocal/multiphoton microscope with superresolution capabilities, a fluorescence stereo microscope and a research quality microwave. The manager for this location is Patty Jansma.
The Life Sciences North location features a dedicated superresolution fluoresence microscope (structured illumination, SIM), an inverted multifunction widefield microscope (color brightfield, polarized light, fluorescence), and an image analysis workstation. The manager for this location is Doug Cromey.
