University of Arizona
Douglas Cromey
1333 N Martin Ave
Tucson, AZ 85721
http://microscopy.arizona.edu/facility/imaging-cores-optical
RRID: RRID:SCR_023355
Confocal Microscopy
Confocal/ Super Resolution Microscope
Fluorescence Microscope With Optical Sectioning Capability
Image Aquisition
Image Processing And Analysis
Microscopy
Multiphoton Microscopy
Multiphoton/ Harmonic Generation Microscope
Stereomicroscopy
Super-resolution Microscopy
Widefield Microscopy
1.) Escoto A, Hecksel R, Parkinson C, Crane S, Atwell B, King S, Ortiz Chavez D, Jannuzi A, Sands B, Bitler BG, Fehniger TA, Paek AL, Padi M, Schroeder J (2025 Feb). Nuclear EGFR in breast cancer suppresses NK cell recruitment and cytotoxicity. Oncogene, 44(5), 288-295. doi: 10.1038/s41388-024-03211-0. PMID: 39521886.
2.) Hostler AC, Hahn WW, Hu MS, Rennert R, Fischer KS, Barrera JA, Duscher D, Januszyk M, Henn D, Sivaraj D, Yasmeh JP, Kussie HC, Granoski MB, Padmanabhan J, Vial IN, Riegler J, Wu JC, Longaker MT, Chen K, Maan ZN, Gurtner GC (2024 Dec 13). Endothelial-specific CXCL12 regulates neovascularization during tissue repair and tumor progression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 38(24), e70210. doi: 10.1096/fj.202401307R. PMID: 39698751.
3.) Bernard K, Mota JA, Wene P, Corenblum MJ, Saez JL, Bartlett MJ, Heien ML, Doyle KP, Polt R, Hay M, Madhavan L, Falk T (2024 Nov). The angiotensin (1-7) glycopeptide PNA5 improves cognition in a chronic progressive mouse model of Parkinson's disease through modulation of neuroinflammation. Experimental neurology, 381(), 114926. doi: 10.1016/j.expneurol.2024.114926. PMID: 39153685.
4.) Hoyer-Kimura C, Hay M, Konhilas JP, Morrison HW, Methajit M, Strom J, Polt R, Salcedo V, Fricks JP, Kalya A, Pires PW (2024 Aug 1). PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia Aging and Disease, 15(4), 1927-1951. . PMCID: 11272189.
5.) Seka DJ, Schulz AK, Thaker TM, Tomasiak TM (2024 May 22). The N-terminal signature motif on the transporter MCT1 is critical for CD147-mediated trafficking The Journal of Biological Chemistry, 300(6), 107333. . PMCID: 11176948.
6.) Lemke MD, Abate AN, Woodson JD (2024 May 3). Investigating the mechanism of chloroplast singlet oxygen signaling in the Arabidopsis thaliana accelerated cell death 2 mutant Plant Signaling & Behavior, 19(1), 2347783. . PMCID: 11073415.
7.) Thota LNR, Lopez Rosales JE, Placencia I, Zemskov EA, Tonino P, Michael AN, Black SM, Chignalia AZ (2023 Sep 26). The Pulmonary Endothelial Glycocalyx Modifications in Glypican 1 Knockout Mice Do Not Affect Lung Endothelial Function in Physiological Conditions. International journal of molecular sciences, 24(19), . . PMID: 37834029.
8.) Lemke MD, Woodson JD (2023). A genetic screen for dominant chloroplast reactive oxygen species signaling mutants reveals life stage-specific singlet oxygen signaling networks. Frontiers in plant science, 14(), 1331346. . PMID: 38273946.
The RII Imaging Cores - Optical facility is a scientific core facility with two locations (Marley, Life Sciences North) dedicated to the acquisition of images for research, industrial and clinical applications. We offer multi-user access to high quality state-of-the-art technologies and cost effective analytical services.
The Marley location features an inverted point scanning confocal microscope, an upright confocal/multiphoton microscope with superresolution capabilities, a fluorescence stereo microscope and a research quality microwave. The manager for this location is Patty Jansma.
The Life Sciences North location features a dedicated superresolution fluoresence microscope (structured illumination, SIM), an inverted multifunction widefield microscope (color brightfield, polarized light, fluorescence), and an image analysis workstation. The manager for this location is Doug Cromey.
