Montpellier GenomiX

Contact Info:

Laurent Journot

c/o IGF, 141 rue de la Cardonille

Montpellie 34090

https://www.mgx.cnrs.fr

Grants and Identifiers:

RRID: RRID:SCR_023091

Instrumentation:

Services Provided:

10x Genomics

ATAC

ATAC-Seq

Bisulfite Conversion

ChIP-Seq

Custom Library Prep Service

Data Analysis And Interpretation

Data Processing And Interpretation

Digital PCR

DNA Isolation

Droplet Digital PCR

Genome/Transcriptome Assembly And Annotation

Genomics

Genotyping

Genotyping-by-sequencing

Long Read Sequencing

Methylation Analysis

Microarray

Nanopore Sequencing

Quantitative DNA Sequence Mapping

Real-time qPCR

RNAseq

Sample Preparation

Sequencing - Capillary Sequencing

Sequencing - DNA Sequencing

Sequencing - Next Generation Sequencing (NGS)

Single-Cell Analysis

Single-cell Sequencing

Whole Exome Sequencing

Whole Genome Sequencing

Relevant Publications:

1.) Pieri A, Beleggia R, Gioia T, Tong H, Di Vittori V, Frascarelli G, Bitocchi E, Nanni L, Bellucci E, Fiorani F, Pecchioni N, Marzario S, De Quattro C, Limongi AR, De Vita P, Rossato M, Schurr U, David JL, Nikoloski Z, Papa R (2024 Sep 3). Transcriptomic response to nitrogen availability reveals signatures of adaptive plasticity during tetraploid wheat domestication. The Plant cell, 36(9), 3809-3823. . PMID: 39056474.

2.) Gaucher J, Montellier E, Vial G, Chuffart F, Guellerin M, Bouyon S, Lemarie E, Botté YY, Dirani A, Ben Messaoud R, Faure MJ, Ribuot DG, Costentin C, Tamisier R, Botté CY, Khochbin S, Rousseaux S, Pépin JL (2024 Feb 16). Long-term intermittent hypoxia in mice induces inflammatory pathways implicated in sleep apnea and steatohepatitis in humans. iScience, 27(2), 108837. . PMID: 38303705.

3.) de la Fuente C, Grondin A, Sine B, Debieu M, Belin C, Hajjarpoor A, Atkinson JA, Passot S, Salson M, Orjuela J, Tranchant-Dubreuil C, Brossier JR, Steffen M, Morgado C, Dinh HN, Pandey BK, Darmau J, Champion A, Petitot AS, Barrachina C, Pratlong M, Mounier T, Nakombo-Gbassault P, Gantet P, Gangashetty P, Guedon Y, Vadez V, Reichheld JP, Bennett MJ, Kane NA, Guyomarc'h S, Wells DM, Vigouroux Y, Laplaze L (2024 Jan 31). Glutaredoxin regulation of primary root growth is associated with early drought stress tolerance in pearl millet. eLife, 12(), . . PMID: 38294329.

4.) Lebdy R, Canut M, Patouillard J, Cadoret JC, Letessier A, Ammar J, Basbous J, Urbach S, Miotto B, Constantinou A, Abou Merhi R, Ribeyre C (2023 Dec 6). The nucleolar protein GNL3 prevents resection of stalled replication forks. EMBO reports, 24(12), e57585. . PMID: 37965896.

5.) Akkawi C, Feuillard J, Diaz FL, Belkhir K, Godefroy N, Peloponese JM, Mougel M, Laine S (2023 Sep 12). Murine leukemia virus (MLV) P50 protein induces cell transformation via transcriptional regulatory function. Retrovirology, 20(1), 16. . PMID: 37700325.

6.) Boulanger M, Aqrouq M, Tempé D, Kifagi C, Ristic M, Akl D, Hallal R, Carusi A, Gabellier L, de Toledo M, Sigurdsson JO, Kaoma T, Andrieu-Soler C, Forné T, Soler E, Hicheri Y, Gueret E, Vallar L, Olsen JV, Cartron G, Piechaczyk M, Bossis G (2023 Sep 8). DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias. Nucleic acids research, 51(16), 8413-8433. . PMID: 37462077.

7.) van der Lans SPA, Janet-Maitre M, Masson FM, Walker KA, Doorduijn DJ, Janssen AB, van Schaik W, Attrée I, Rooijakkers SHM, Bardoel BW (2023 Aug 3). Colistin resistance mutations in phoQ can sensitize Klebsiella pneumoniae to IgM-mediated complement killing. Scientific reports, 13(1), 12618. . PMID: 37537263.

8.) King E, Wallner A, Guigard L, Rimbault I, Parrinello H, Klonowska A, Moulin L, Czernic P (2023 Jul 3). Paraburkholderia phytofirmans PsJN colonization of rice endosphere triggers an atypical transcriptomic response compared to rice native Burkholderia s.l. endophytes. Scientific reports, 13(1), 10696. . PMID: 37400579.

Description:

MGX (Montpellier GenomiX) offers cutting-edge genomic technologies to academic laboratories and biotechnology companies. Application portfolio includes : Whole genome (re)sequencing, including the identification of variants (SNVs, mutations, indels, CNVs), Targeted sequencing, for instance exomes, Transcriptome analyses (RNA-Seq, small RNA-Seq, microarrays), including in single cells (single-cell 3’RNA-seq) Determination of chromatin structure and dynamics (ChIP-Seq, FAIRE-Seq, Hi-C), Epigenetic analyses (ChIP-Seq, RRBS, Bisulphite-Seq), Genotyping (RAD-Seq, GBS, microarrays).