Cincinnati Children's Hospital
Kathryn Wikenheiser-Brokamp
3333 Burnet Avenue
Cincinnati, OH 45229-3026
https://www.cincinnatichildrens.org/research/cores/pathology-core
RRID: RRID:SCR_022637
1.) Halurkar MS, Inoue O, Singh A, Mukherjee R, Ginugu M, Ahn C, Bonatto Paese CL, Duszynski M, Brugmann SA, Lim HW, Sanchez-Gurmaches J (2025 Jan 17). The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes. Nature communications, 16(1), 770. . PMID: 39824816.
2.) Tominaga K, Kechele DO, Sanchez JG, Vales S, Jurickova I, Roman L, Asai A, Enriquez JR, McCauley HA, Kishimoto K, Iwasawa K, Singh A, Horio Y, Múnera JO, Takebe T, Zorn AM, Helmrath MA, Denson LA, Wells JM (2024 Dec 17). Deriving Human Intestinal Organoids with Functional Tissue-Resident Macrophages All From Pluripotent Stem Cells Cellular and Molecular Gastroenterology and Hepatology, 19(4), 101444. . PMCID: 11847122.
3.) Dai Q, Preusse K, Yu D, Kovall RA, Thorner K, Lin X, Kopan R (2024 Dec 12). Loss of Notch dimerization perturbs intestinal homeostasis by a mechanism involving HDAC activity PLOS Genetics, 20(12), e1011486. . PMCID: 11670933.
4.) Culver-Cochran AE, Hassan A, Hueneman K, Choi K, Ma A, VanCauwenbergh B, O’Brien E, Wunderlich M, Perentesis JP, Starczynowski DT (2024 Oct 24). Chemotherapy resistance in acute myeloid leukemia is mediated by A20 suppression of spontaneous necroptosis Nature Communications, 15(), 9189. . PMCID: 11502881.
5.) Shi M, Crouse B, Sundaram N, Pode Shakked N, Ester L, Zhang W, Janakiram V, Kopan R, Helmrath MA, Bonventre JV, McCracken KW (2024 Sep 20). Integrating collecting systems in kidney organoids through fusion of distal nephron to ureteric bud bioRxiv, (), 2024.09.19.613645. . PMCID: 11429897.
6.) Sheth M, Sharma M, Lehn M, Reza H, Takebe T, Takiar V, Wise-Draper T, Esfandiari L (2024 Sep). Three-dimensional matrix stiffness modulates mechanosensitive and phenotypic alterations in oral squamous cell carcinoma spheroids. APL bioengineering, 8(3), 036106. . PMID: 39092008.
7.) Al Reza H, Santangelo C, Al Reza A, Iwasawa K, Sachiko S, Glaser K, Bondoc A, Merola J, Takebe T (2024 Aug 30). Self-Assembled Generation of Multi-zonal Liver Organoids from Human Pluripotent Stem Cells bioRxiv, (), 2024.08.30.610426. . PMCID: 11384014.
8.) DeVore SB, Schuetz M, Alvey L, Lujan H, Ochayon DE, Williams L, Chang WC, Filuta A, Ruff B, Kothari A, Hahn JM, Brandt E, Satish L, Roskin K, Herr AB, Biagini JM, Martin LJ, Cagdas D, Keles S, Milner JD, Supp DM, Khurana Hershey GK (2024 Aug 27). Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease. Cell reports, 43(8), 114589. . PMID: 39110589.
9.) Stepanchick E, Wilson A, Sulentic AM, Choi K, Hueneman K, Starczynowski DT, Chlon TM (2024 Aug). DDX41 haploinsufficiency causes inefficient hematopoiesis under stress and cooperates with p53 mutations to cause hematologic malignancy. Leukemia, 38(8), 1787-1798. . PMID: 38937548.
10.) Peters AL, DePasquale EAK, Begum G, Roskin KM, Woodle ES, Hildeman DA (2024 Feb 29). Defining the T cell transcriptional landscape in pediatric liver transplant rejection at single cell resolution. bioRxiv : the preprint server for biology, (), . . PMID: 38464256.
11.) Kissell LN, Liu H, Sheokand M, Vang D, Kachroo P, Strobbia P (2024 Jan 26). Direct Detection of Tobacco Mosaic Virus in Infected Plants with SERS-Sensing Hydrogels. ACS sensors, 9(1), 514-523. doi: 10.1021/acssensors.3c02537. PMID: 38195409.
12.) Huo J, Prasad V, Grimes KM, Vanhoutte D, Blair NS, Lin SC, Bround MJ, Bers DM, Molkentin JD (2023 Nov 28). MCUb is an inducible regulator of calcium-dependent mitochondrial metabolism and substrate utilization in muscle. Cell reports, 42(11), 113465. . PMID: 37976157.
13.) Múnera JO, Kechele DO, Bouffi C, Qu N, Jing R, Maity P, Enriquez JR, Han L, Campbell I, Mahe MM, McCauley HA, Zhang X, Sundaram N, Hudson JR, Zarsozo-Lacoste A, Pradhan S, Tominaga K, Sanchez JG, Weiss AA, Chatuvedi P, Spence JR, Hachimi M, North T, Daley GQ, Mayhew CN, Hu YC, Takebe T, Helmrath MA, Wells JM (2023 Nov 2). Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon Cell stem cell, 30(11), 1434-1451.e9. . PMCID: 10913028.
14.) Reza HA, Farooqui Z, Reza AA, Conroy C, Iwasawa K, Ogura Y, Okita K, Osafune K, Takebe T (2023 Oct 12). Synthetic augmentation of bilirubin metabolism in human pluripotent stem cell-derived liver organoids Stem Cell Reports, 18(11), 2071-2083. . PMCID: 10679658.
15.) Doll JR, Moreno-Fernandez ME, Stankiewicz TE, Wayland JL, Wilburn A, Weinhaus B, Chougnet CA, Giordano D, Cappelletti M, Presicce P, Kallapur SG, Salomonis N, Tilburgs T, Divanovic S (2023 Apr 25). BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth. Cell reports, 42(4), 112352. . PMID: 37027297.
16.) Khorki ME, Shi T, Cianciolo EE, Burg AR, Chukwuma PC, Picarsic JL, Morrice MK, Woodle ES, Maltzman JS, Ferguson A, Katz JD, Baker BM, Hildeman DA (2023). Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts. Frontiers in immunology, 14(), 1287546. . PMID: 38143762.
The Integrated Pathology Research Facility provides advanced tissue and morphologic services with consultation to enable routine and state-of-the-art technologies. The Facility personnel are dedicated to making every researcher feel confident that their projects will be held to the highest of standards with attention to detail and quality results that are not only diagnostic but publication worthy.
