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University of Pennsylvania Perelman School of Medicine Molecular Pathology and Imaging Core (MPIC)

University of Pennsylvania

Contact Info:

Jonathan Katz

https://www.med.upenn.edu/CMSDLD/the-molecular-pathology-and-imaging-core-mpic.html

Grants and Identifiers:

RRID: RRID:SCR_022420

Instrumentation:

Services Provided:

Relevant Publications:

1.) Hsieh CJ, Saturnino Guarino D, Young AJ, Siderowf AD, Nasrallah I, Schmitz A, Garcia C, Kim HY, Schubert EK, Lee H, Perlmutter JS, Mach RH (2025 Jul 26). Pilot Study of [11C]HY-2-15: A Mixed Alpha-Synuclein and Tau PET Radiotracer Cells, 14(15), 1157. . PMCID: 12346455.


2.) Noji MC, Demetriadou C, Landis M, Pennise J, Pinheiro LV, Jaccard A, Chatoff A, Drummond J, Guo K, Azor R, Robertson MR, Kawakami R, Marcinkiewicz MM, Tobias JW, Snyder NW, Feldser D, Arany Z, Wellen KE (2025 Jun 15). Opposing effects of systemic and pancreas-specific inhibition of BCKDK on pancreatic carcinogenesis bioRxiv, (), 2025.06.10.658925. . PMCID: 12259105.


3.) Gautam R, Lal M, Carroll MC, Mrozek Z, Trachsel T, Beers J, Ruffner MA (2024 Aug 23). Proton pump inhibitors modulate esophageal epithelial barrier function and crosstalk with eosinophils bioRxiv, (), 2024.08.22.609219. . PMCID: 11370561.


4.) Xiao Z, Todd L, Huang L, Noguera-Ortega E, Lu Z, Huang L, Kopp M, Li Y, Pattada N, Zhong W, Guo W, Scholler J, Liousia M, Assenmacher CA, June CH, Albelda SM, Puré E (2023 Aug 22). Desmoplastic stroma restricts T cell extravasation and mediates immune exclusion and immunosuppression in solid tumors Nature Communications, 14(), 5110. . PMCID: 10444764.


Description:

Provides histological services, equipment, and technical expertise for processing and analyses of digestive, pancreatic, and liver tissues as well as three dimensional tissue culture models. Part of the Center for Molecular Studies in Digestive and Liver Diseases