University of Pennsylvania
Chris Petucci
https://www.med.upenn.edu/cvi/metabolomics-core.html
RRID: RRID:SCR_022381
1.) Markosyan N, Kim IK, Arora C, Quinones-Ware L, Joshi N, Cheng N, Schechter EY, Tobias JW, Hochberg JE, Corse E, Liu K, Rodriguez DiBlasi V, Chan LC, Smyth EM, FitzGerald GA, Stanger BZ, Vonderheide RH (2024 Nov 8). Pivotal roles for cancer cell–intrinsic mPGES-1 and autocrine EP4 signaling in suppressing antitumor immunity JCI Insight, 9(21), e178644. . PMCID: 11601572.
2.) Weissenrieder JS, Peura J, Paudel U, Bhalerao N, Weinmann N, Johnson C, Wengyn M, Drager R, Furth EE, Simin K, Ruscetti M, Stanger BZ, Rustgi AK, Pitarresi JR, Foskett JK (2024 Aug 9). Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity bioRxiv, (), 2024.08.08.607195. . PMCID: 11326289.
3.) Naeem F, Leone TC, Petucci C, Shoffler C, Kodihalli RC, Hidalgo T, Tow-Keogh C, Mancuso J, Tzameli I, Bennett D, Groarke JD, Flach RJ, Rader DJ, Kelly DP (2024 Jul 25). Targeted Quantitative Plasma Metabolomics Identifies Metabolite Signatures that Distinguish Heart Failure with Reduced and Preserved Ejection Fraction medRxiv, (), 2024.07.24.24310961. . PMCID: 11302718.
4.) Flores-Mendez M, Ohl L, Roule T, Zhou Y, Tintos-Hernández JA, Walsh K, Ortiz-González XR, Akizu N (2024 Jan 22). IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency bioRxiv, (), 2024.01.20.576443. . PMCID: 10849482.
Core is overseen by Cardiovascular Institute and is partnership with the Abramson Cancer Center and the Institute for Diabetes, Obesity and Metabolism at Penn. Provides expertise in targeted and untargeted metabolomics of biological samples using liquid chromatography/mass spectrometry. Performs assays and assists in interpretation of results.
