University of Pennsylvania

Contact Info:

Jorge Henao-Mejia

https://med-upenn.corefacilities.org/sc/4405/crispr-cas9-mouse-targeting-core/?tab=about

Grants and Identifiers:

RRID: RRID:SCR_022378

Instrumentation:

Services Provided:

Relevant Publications:

1.) Cheslow L, Byrne M, Kopenhaver JS, Iacovitti L, Smeyne RJ, Snook AE, Waldman SA (2023 Oct 13). GUCY2C signaling limits dopaminergic neuron vulnerability to toxic insults Research Square, (), rs.3.rs-3416338. . PMCID: 10602097.

2.) Barton JR, Londregran AK, Alexander TD, Entezari AA, Bar-Ad S, Cheng L, Lepore AC, Snook AE, Covarrubias M, Waldman SA (2023 Feb 15). Intestinal neuropod cell GUCY2C regulates visceral pain The Journal of Clinical Investigation, 133(4), e165578. . PMCID: 9927949.

Description:

Core facilitates use of CRISPR/Cas9 genome editing technology to generate novel mouse genetic tools.