University of Miami

Contact Info:

George Grills

https://umiamihealth.org/sylvester-comprehensive-cancer-center/research/research-resources/shared-resources/cancer-proteomics-shared-resource

Grants and Identifiers:

RRID: RRID:SCR_028491

Instrumentation:

Services Provided:

Relevant Publications:

Description:

Core provides advanced mass spectrometry-based proteomics to support basic, translational, and clinical cancer research. Delivers high quality, quantitative proteomic data using instrumentation, including Thermo Scientific Astral Zoom and Ascend Tribrid orbitrap mass spectrometers. Services include gel band protein identification, immunoprecipitation and pulldown proteomics, cleavable cross-linking mass spectrometry, and global quantitative proteomics and post‑translational modification analysis using tandem mass tag‑based multiplexing or label‑free data-independent acquisition and data-dependent acquisition approaches. The CPSR supports end-to-end proteomics pipelines—from whole cells and primary tumor organoids through quantitative analysis and data visualization—providing comprehensive “soup to nuts” analytical capability.