Mayo Clinic
Contact Info:
GAC Supervisors
200 First St. SW
Stabile 13-20
Rochester, MN 55905
https://www.mayo.edu/research/core-resources/genome-analysis-core/overview
Grants and Identifiers:
RRID: RRID:SCR_028327
Instrumentation:
10X Genomics Chromium X Single Cell Analyzer
Analyzer used for high throughput full range single cell analysis. Chromium X runs high-throughput assays. It runs all single cell assays, including high-throughput assays for Single Cell Immune Profiling and Single Cell Gene Expression. [Product Link]
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Agilent 2100 Bioanalyzer Instrument
This Bioanalyzer Instrument is used for sample quality control of biomolecules. [Product Link]
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Agilent 4200 TapeStation System
TapeStation System is used to analyze DNA and RNA samples for quality control. [Product Link]
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Agilent Bravo NGS Workstation
Automated liquid handling robot preconfigured for library prep and enrichment when using next generation sequencing NGS protocols. [Product Link]
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Agilent Femto Pulse System
Femto Pulse System separates large molecular weight DNA fragments and detects nucleic acids into femtogram range. [Product Link]
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Hamilton Microlab STAR Automated Liquid Handling
STAR Automated Liquid Handling uses pipetting technology to achieve high accuracy, precision, and repeatability from sub-microliter to large volumes. [Product Link]
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(Equipment No Longer Active At this Facility)
Hamilton NGS STAR for Library Prep Asssay Ready Workstation
NGS STAR for Library Prep is used for Massive Parallel Sequencing. [Product Link]
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Illumina iScan System
Can scan thousands of array samples per day, without sacrificing data quality or reproducibility. [Product Link]
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Illumina NextSeq 2000 system
Sequencing system supports range of methods such as exome sequencing, target enrichment, single-cell profiling. [Product Link]
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Illumina NovaSeq X Plus
NovaSeq X Plus Sequencing System has ability to sequence more than 128 genomes per run. Provides faster run times, and the ability to process data directly on the instrument. Uses dual flow cells. Production scale sequencing system can also perform broad range of data intensive applications, from single-cell analysis to exome and circulating tumor DNA sequencing. [Product Link]
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PromethION
System offers real-time, long-read, direct DNA and RNA sequencing by Oxford Nanopore Technologies. System suitable for large scale projects such as population-scale sequencing or plant genomics, or for large scale service offerings. PromethION 24 and PromethION 48 systems offer ability to run 24 and 48 flow cells respectively. System allows on demand sequencing, using any flow cell at any time. Users can start and stop running individual experiments as required, or deploy multiple flow cells onto single experiments for greater speed or throughput. [Product Link]
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Revvity SciClone G3 liquid handling workstation
Advanced automated liquid handling platform originally developed by PerkinElmer. Designed and programmed for next generation sequencing (NGS) applications. They feature library of over 120 pre-developed and verified or vendor qualified automated NGS preparation kits. [Product Link]
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Sage Science BluePippin system
Used for DNA Size Selection for Next-Gen Sequencing, with Pulsed-Field (100bp ? 50kb).BluePippin has the DNA capabilities of the Pippin Prep, plus the extra benefit of pulsed-field electrophoresis for resolving and collecting high molecular weight DNA. For long-range genomic applications, high-pass filtering allows users to collect all fragments above a size threshold set by the user. Target sizes or ranges of sizes are entered in software, and fractions are collected in buffer. Up to 5 samples/gel cassette may be run, with no possibility of cross contamination. [Product Link]
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SpectraMax iD3 multi-mode microplate reader
Microplate reader to measure absorbance, fluorescence and luminescence. [Product Link]
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Pacific Biosciences Revio
Long-read sequencing platform using PacBio’s SMRT (Single Molecule, Real-Time) technology to generate highly accurate HiFi reads
Tecan Freedom EVO Robotic Workstation
Liquid handling system used in conjunction with Illumina's Infinium workflow
Tecan Infinium Automated Pipetting System (IAPS) with ILASS
Tecan-based, Illumina-certified automation system for Infinium assays
(Equipment No Longer Active At this Facility)
Tecan Tecan Infinium Automated Pipetting System (IAPS) with ILASS
Tecan-based, Illumina-certified automation system for Infinium assays
Services Provided:
Illumina Short-read Sequencing
Relevant Publications:
Description:
The Genome Analysis Core provides comprehensive, world-class services supported by state-of-the-art technology and deep scientific expertise. We partner with researchers at every stage of a project, offering end-to-end solutions from assisting with experimental design to sample preparation and genomic analyses.
