Massachusetts General Hospital

Contact Info:

Mohammed Mahamdeh

https://mic.massgeneralbrigham.org

Grants and Identifiers:

RRID: RRID:SCR_027865

Instrumentation:

Services Provided:

Relevant Publications:

1.) Mnatsakanyan H, Sammarco A, Hewett A, Awwad R, Roumieh E, Pechdimaljian C, Cakici C, Spangler CM, Azar Y, Pradhan R, Su B, Williams KJ, Bensinger SJ, Badr CE (2026 Apr 13). SCD1 and SCD5 modulate PARP-dependent DNA repair via fatty acid desaturation in glioblastoma. Cell reports, 45(4), 117223. . PMCID: 13181748.

2.) Lark ARS, Mir FA, Ambareen N, Tian F, Carpenter AH, Crowley EA, Toro BA, Syme CE, Aygar S, Thendral A, Smith K, White CG, Mahamdeh MS, Choi J, Nehs CJ (2026). Ketogenic interventions enhance REM sleep in females and support memory in aged rats. Frontiers in aging neuroscience, 18(), 1797686. . PMCID: 13106476.

Description:

Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.