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MSKCC-Structural Biology Core Facility

Memorial Sloan Kettering Cancer Center

Contact Info:

Jason De La Cruz

430 E 67th Street

Rockefeller Research Laboratories

New York, NY 10065

https://www.mskcc.org/research/ski/core-facilities/structural-biology

Grants and Identifiers:

RRID: RRID:SCR_027809

Instrumentation:

Services Provided:

Relevant Publications:

Description:

Core provides expertise, advanced equipment, and leading software to support structural investigations. Core maintains equipment, including Krios cryogenic electron microscopes and computational resources for data collection, processing, and structure determination. These resources include graphical workstations and high-performance Linux cluster, supporting the analysis of large proteins, complexes, and macromolecular assemblies.Core has access to synchrotron beamlines and cryo-EM facilities.Provides training and assistance to users, collaborates with non-structural MSK groups on projects involving macromolecular crystallization and structure determination, offers modeling expertise and guidance, enabling labs to use available structural data in experiment design and interpretation.