Memorial Sloan Kettering Cancer Center
Contact Info:
Jason De La Cruz
430 E 67th Street
Rockefeller Research Laboratories
New York, NY 10065
https://www.mskcc.org/research/ski/core-facilities/structural-biology
Grants and Identifiers:
RRID: RRID:SCR_027809
Instrumentation:
Services Provided:
Relevant Publications:
Description:
The SBio Core provides expertise, advanced equipment, and leading software to support structural investigations. The Core maintains cryoEM equipment, including two Krios electron microscopes and computational resources for data collection, processing, and structure determination. These resources include graphical workstations and integration with MSK’s high-performance computing clusters, supporting the analysis of large proteins, complexes, and macromolecular assemblies. The Core also has biochemistry and crystallography expertise, as well as access to synchrotron beamlines at Brookhaven National Laboratory and Argonne National Laboratory. The Core provides training and assistance to users, collaborates with MSK groups on projects involving macromolecular crystallization and structure determination, and offers modeling expertise and guidance, thereby enabling labs to use available structural data in experiment design and interpretation.
