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Memorial Sloan Kettering Cancer Center Research Pharmacy Core Facility

Memorial Sloan Kettering Cancer Center

Contact Info:

Scott Freeswick

https://www.mskcc.org/research/ski/core-facilities/research-pharmacy

Grants and Identifiers:

RRID: RRID:SCR_027807

Instrumentation:

Services Provided:

Relevant Publications:

Description:

Core is a full-service facility that prepares agents developed by MSK researchers to be used as investigational drugs in preclinical or clinical studies. The Core comprises three principal groups: the Pharmaceutical Product Facility (PPF) for drug formulation/stability and preparation; the Clinical Grade Production (CGP) Facility for bulk product manufacturing, purification, and vialing; and the Pharmacy Investigational Drug Service (PIDS), which develops, procures, prepares, and validates the preparation, packaging, and distribution of investigational drugs for clinical use. Core services include: formulation, analysis, and evaluation of drug release rates; prediction of interactions; and determinations of compatibility and physical stability of medications. Based on the expertise of the RP Core, MSK has been able to bring into early-phase clinical trials multiple types of pharmacologic agents, including traditional small molecules, radiopharmaceuticals, and vaccines.