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MSKCC-Mouse Genetics Core Facility

Memorial Sloan Kettering Cancer Center

Contact Info:

Yas Furuta

430 E 67th Street

New York, NY 10065

https://www.mskcc.org/research/ski/core-facilities/mouse-genetics

Grants and Identifiers:

RRID: RRID:SCR_027803

Instrumentation:

Services Provided:

Assisted Reproduction

GEM Cryo-archiving/rederivation

GEM Strategies/reagents

Genome Editing

Mouse Embryonic Stem Cells

Provision Of Mouse Strains

Transgenic Mouse

Relevant Publications:

Description:

Mouse Genetics Core Facility (MGCF) provides technical support to facilitate the generation and utilization of genetically engineered mouse (GEM) models for MSK investigators and the surrounding biomedical research community. The services provided by MGCF encompass three broad areas of expertise; 1) molecular and cell biology platforms cover design and assembly of genome engineering reagents, such as CRISPR/Cas9 and genetically engineered mouse embryonic stem (ES) cells; 2) these reagents are then brought into sophisticated mouse embryo micromanipulation platforms to generate GEM models; and 3) reproductive- and cryo-biology platforms allow for rapid GEM cohort expansion, rederivation of GEM lines, and GEM resource archiving. MGCF also provides consultation and training for wide aspects of GEM model development and application to aid in successful GEM projects.