Memorial Sloan Kettering Cancer Center

Contact Info:

IGO Team

1250 1st Avenue

Arnold and Marie Schwartz Cancer Research Building, 7th Floor

New York, NY 10065

https://www.mskcc.org/research/ski/core-facilities/integrated-genomics-operation-igo

Grants and Identifiers:

RRID: RRID:SCR_027801

Instrumentation:

Services Provided:

Bulk Genomics & Transcriptomics

Digital PCR

Long Read Sequencing

Nucleic Acid Extraction

Sequencing

Single Cell & Spatial Transcriptomics

TCR Sequencing

Relevant Publications:

1.) Hinterleitner C, Barthet VJA, Goldberg HV, Vogt KC, Perea AM, Ruiz S, Hillger LR, McHugh D, Ho YJ, Chaves-Perez A, Skamagki M, Flowers S, Rekhtman N, Zhuang X, Barretto GD, Li X, Watson JT, Luan W, Simon J, Tammela T, Gardner R, Rudin CM, Romesser PB, Bott MJ, Filliol A, Heller DA, Lowe SW (2026 Mar 4). Senescence-directed nanotherapy ameliorates fibrosis and overcomes immune exclusion in cancer. bioRxiv : the preprint server for biology, (), . . PMCID: 13001502.

Description:

The IGO provides services and expertise to Center investigators interested in evaluating gene expression, chromosome structure, and nucleotide sequence on a broad scale. Enables basic, clinical, and translational research projects across the Center. Through its production group, the Core enables genomic and transcriptomic analyses and has the expertise to process challenging samples from all origins (tissue, dissociated single cells and cell pellets, paraffin curls, blood, serum, etc.). Bulk DNA/RNA assays operate in highly automated environment, from sample reception to sequencing library preparation.