Augusta University
Wenbo Zhi
https://www.augusta.edu/research/core/proteomics.php
RRID: RRID:SCR_027673
1.) Alhamad DW, Bensreti H, Ding K, Sultana S, Yearwood CL, Ellingwood A, Shaver J, Burkhart K, Tripathi A, Dorn J, Cushing M, Nesbit H, Dai C, Morey E, Gross C, Alhamad M, Taylor D, Cherezova A, Ilatovskaya DV, Zhi W, Cooley MA, Zhong R, Johnson MH, Bollag WB, Hamrick MW, Fulzele S, Hill WD, Isales CM, McGee-Lawrence ME (2026 Jan 22). Tryptophan metabolites 3-hydroxykynurenine (3HK) and 3-hydroxyanthranilic acid (3HAA) increase oxidative stress and impair osteoblastic bone formation. The Journal of biological chemistry, 302(4), 111174. . PMCID: 13018973.
2.) Kuppuswamy S, Watson NJ, Ledford WL, Pavri BA, Zhi W, Gbadebo M, Bonsack F, Xu H, Sukumari-Ramesh S (2025 Aug). Brain proteome changes after intracerebral hemorrhage in aged male and female mice. Neurobiology of disease, 212(), 106936. . PMID: 40320180.
3.) Xi C, Pang J, Xue W, Cui Y, Jiang N, Zhi W, Shi H, Horuzsko A, Pace BS, Zhu X (2025 Jan 6). Transsulfuration pathway activation attenuates oxidative stress and ferroptosis in sickle primary erythroblasts and transgenic mice. Communications biology, 8(1), 15. . PMID: 39762627.
4.) Jaiyesimi O, Kuppuswamy S, Zhang G, Batan S, Zhi W, Ganta VC (2024 Aug). Glycolytic PFKFB3 and Glycogenic UGP2 Axis Regulates Perfusion Recovery in Experimental Hind Limb Ischemia. Arteriosclerosis, thrombosis, and vascular biology, 44(8), 1764-1783. . PMID: 38934117.
5.) Crivelli SM, Quadri Z, Elsherbini A, Vekaria HJ, Sullivan PG, Zhi W, Martinez-Martinez P, Spassieva SD, Bieberich E (2024). Abnormal Regulation of Mitochondrial Sphingolipids during Aging and Alzheimer's Disease. ASN neuro, 16(1), 2404367. . PMID: 39499163.
Facility for characterization and expression level quantitation of proteins (isolated or in an extract) and small molecules/metabolites by mass spectrometry (MS) and/or chromatography. Services include protein identification, labeled and label-free comparative proteomics by Orbitrap mass spectometry, protein/small molecule quantification using targeted mass spectometry (PRM and SRM/MRM mass spectometry), high throughput protein immune-protein assays (384-well Luminex/ELISA assay), etc.
