Cleveland Clinic

Contact Info:

Dr. Stauffer

https://www.lerner.ccf.org/therapeutics-discovery/

Grants and Identifiers:

RRID: RRID:SCR_027386

Instrumentation:

Services Provided:

Relevant Publications:

Description:

Core to promote translation of basic science discoveries by Cleveland Clinic researchers into new therapeutics. Through collaboration with investigators we de-risk promising approaches and illuminate fundamental biology using small molecule chemical probes. We have established a pipeline of innovative research programs directed toward improving patient care with a true bench-to-bedside vision. To achieve these goals, we use state of the art technologies in small molecule library screening, fragment-based methods, X-ray crystallography, computational tools, and target validation towards generating starting points for nascent hit-to-lead and lead optimization campaigns.