University of Miami

Contact Info:

Brooke DeRosa

https://med.miami.edu/centers-and-institutes/hihg/research-centers/center-for-molecular-genetics/induced-pluripotent-stem-cell-core

Grants and Identifiers:

RRID: RRID:SCR_026969

Instrumentation:

Services Provided:

Relevant Publications:

1.) Cukier HN, DeRosa BA, Coombs LE, Tang E, Leyva DR, Lazzaro AR, Gu E, Dykxhoorn DM, Haines JL, Pericak-Vance MA, Song YE, Bush WS, Griswold AJ (2025 Oct 9). Generation of two isogenic induced pluripotent stem cell lines derived from a Hispanic individual with Alzheimer’s Disease and mosaic for loss of the Y chromosome Stem cell research, 89(), 103851. . PMCID: 12818727.

Description:

Core provides standardized services for derivation and characterization of human iPSC lines from peripheral blood and tissue samples. Offerings include PBMC isolation, reprogramming, Sendai virus reprogramming vector removal and analysis, karyotyping, mycoplasma testing, in vitro differentiation of neural and hemopoietic progenitor cells, and immunocytochemical staining of cell type markers and imaging. Core additionally offers hands-on training and consultation to support the use of iPSC technologies in disease modeling.