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University of Wisconsin-Madison Intellectual and Developmental Disabilities Models Core Facility

University of Wisconsin–Madison

Contact Info:

John Svaren

https://www.waisman.wisc.edu/idd-models/

Grants and Identifiers:

RRID: RRID:SCR_026781

Instrumentation:

Services Provided:

Relevant Publications:

1.) Gao Y, Dong Q, Arachchilage KH, Risgaard RD, Syed M, Sheng J, Schmidt DK, Jin T, Liu S, Sandoval SO, Knaack S, Eckholm MT, Chen RJ, Guo Y, Doherty D, Glass I, Levine JE, Wang D, Chang Q, Zhao X, Sousa AMM (2025 Aug 6). Multimodal analyses reveal genes driving electrophysiological maturation of neurons in the primate prefrontal cortex. Neuron, 113(15), 2490-2507.e16. . PMCID: 12331439.


Description:

Models Core in Waisman Center provides resources including mouse models of human conditions, along with behavioral testing capabilities to characterize these models and test new therapies; stem cell technologies to support creation of induced pluripotent stem cell lines for IDD conditions as well as specialized genome editing services; microscopy technology and expertise for characterization of both stem cell and mouse models of IDD conditions.