Pennsylvania State University

Contact Info:

Neela Yennawar

https://www.huck.psu.edu/core-facilities/x-ray-crystallography-facility

Grants and Identifiers:

RRID: RRID:SCR_024464

Instrumentation:

Services Provided:

Relevant Publications:

1.) Vishweshwaraiah YL, Hnath B, Wang J, Chandler M, Mukherjee A, Yennawar NH, Booker SJ, Afonin KA, Dokholyan NV (2024 May 3). A Piecewise Design Approach to Engineering a Miniature ACE2 Mimic to Bind SARS-CoV-2 ACS applied bio materials, 7(5), 3238-3246. . PMCID: 11586090.

Description:

Facility provides infrastructure and support for investigators to undertake single crystal X-ray structural studies. Provides instrumentation, training, and collaboration for Protein characterization, including dynamic light scattering, differential scanning calorimetry, bio-layer interferometry, and circular dichroism; Binding studies using isothermal titration calorimetry; Robotic crystallization, incubators, UV, and digital microscopes;Robotic imaging; Diffraction data collection and processing; Structure determination and analysis; Molecular modeling; Small angle X-ray scattering. Staff is available to train researchers to use equipment and to assist with project development and research.