Pennsylvania State University
Ashley Shay
https://www.huck.psu.edu/core-facilities/metabolomics-core-facility
RRID: RRID:SCR_023864
1.) Walsh B, Summers RL, Rangel GW, Hagenah LM, Mok S, Llinás M, Fidock DA, Wirth DF, Bopp S (2025 Jul 28). The plasmepsin-piperaquine paradox persists in Plasmodium falciparum PLOS Pathogens, 21(7), e1012779. . PMCID: 12321132.
2.) Jauregui MJ, Warren ER, Di Gioia F, Kwasniewski MT, Lambert JD (2025 Jul 15). Effects of Hot Air Drying on the Nutritional and Phytochemical Composition of Radish (Raphanus sativus L.) Microgreens Journal of Food Science, 90(7), e70426. . PMCID: 12264400.
3.) Alberione MP, Avalos-Padilla Y, Rangel GW, Ramírez M, Romero-Uruñuela T, Fenollar À, Ortega-Barrionuevo J, Crispim M, Smith TK, Llinás M, Izquierdo L (2025 Jul 3). Hexosamine biosynthesis disruption impairs GPI production and arrests Plasmodium falciparum growth at schizont stages PLOS Pathogens, 21(7), e1012832. . PMCID: 12251206.
4.) Rajaram K, Rangel GW, Munro JT, Nair SC, Elahi R, Llinás M, Prigge ST (2025 May 19). Multiple, redundant carboxylic acid transporters support mitochondrial metabolism in Plasmodium falciparum The Journal of Biological Chemistry, 301(7), 110248. . PMCID: 12268629.
5.) Woodland JG, Coertzen D, Wicht KJ, Hidalgo VF, Pasaje CF, Godoy LC, Qahash T, Mmonwa MM, Dziwornu GA, Wambua L, Harries S, Korkor CM, Njoroge M, Krugmann L, Taylor D, Leshabane M, Langeveld H, Rabie T, Reader J, van der Watt M, Venter N, Erlank E, Aswat AS, Koekemoer LL, Yeo T, Jeon JH, Fidock DA, Gamo FJ, Wittlin S, Niles JC, Llinas M, Coulson LB, Birkholtz L, Chibale K (2025 May 15). The ATM Kinase Inhibitor AZD0156 Is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and Is an Attractive Candidate for Medicinal Chemistry Optimization Against Malaria Angewandte Chemie (International Ed. in English), 64(28), e202425206. . PMCID: 12232896.
6.) Patterson A, Boyle N, John J, Wang M, Mannochio-Russo H, Pyo JJ, Kim MS, Tian S, Koo I, Anitha M, Tian Y, Morgan E, Murray I, Perdew G, Wu G, Dorrestein P, Bisanz J, Redinbo M (2025 Apr 8). Glucuronidation Metabolomic Fingerprinting to Map Host-Microbe Metabolism Research Square, (), rs.3.rs-6321321. . PMCID: 12036448.
7.) Tracy KM, Shishido Y, Petrovic M, Murphy A, Adesanya T, Fortier AK, Harris TR, Cortelli M, Tucker WD, François SA, Petree B, Raietparvar K, Simon V, Johnson CA Jr, Simonds E, Poland J, Glomp GA, Crannell C, Liang J, Marshall A, Hinton A Jr, Shaver CM, Demarest CT, Ukita R, Shah AS, Rizzari M, Montenovo M, Rauf MA, McReynolds M, Bacchetta M (2025 Mar 20). 10 degree C static storage of porcine donation after circulatory death livers improves biliary viability and mitigates ischemia-reperfusion injury American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 25(7), 1417-1431. . PMCID: 12221823.
8.) Li S, Liu H, Hu H, Ha E, Prasad P, Jenkins BC, Das US, Mukherjee S, Shishikura K, Hu R, Rader DJ, Pei L, Baur JA, Matthews ML, FitzGerald GA, McReynolds MR, Susztak K (2025 Jan 7). Human genetics identify convergent signals in mitochondrial LACTB-mediated lipid metabolism in cardiovascular-kidney-metabolic syndrome. Cell metabolism, 37(1), 154-168.e7. doi: 10.1016/j.cmet.2024.10.007. PMID: 39561766.
9.) Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E (2024 Nov 1). Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake bioRxiv, (), 2024.10.28.620705. . PMCID: 11566042.
10.) Kellogg JJ, Alonso MN, Jordan RT, Xiao J, Cafiero JH, Bush T, Chen X, Towler M, Weathers P, Shell SS (2024 Oct 28). An O-methylflavone from Artemisia afra kills non-replicating hypoxic Mycobacterium tuberculosis. Journal of ethnopharmacology, 333(), 118500. . PMID: 38944359.
11.) Obare LM, Bailin SS, Zhang X, Nthenge K, Priest S, Liu Q, Stolze LK, Sheng Q, Gangula R, Behrens M, Jenkins B, Prasad P, Neikirk K, Prakash P, Hogan M, Zhang L, Beasley HK, Shao J, Miller-Fleming TW, Actkins KV, Phillips MA, Hubert D, Malone J, Labeeb C, Gelbard A, Chaillon A, Mashayekhi M, Gabriel CL, Temu T, Olson L, Jones A, Beeri K, Baker P, Kawai K, Ghosh SK, Guo L, Virmani R, Finn A, Shah P, Yang TS, Bick AG, Kirabo A, Su YR, Phillips EJ, Mallal S, Dash C, Koethe JR, Gianella S, McReynolds (2024 Oct 18). HIV persists in late coronary atheroma and is associated with increased local inflammation and disease progression Research Square, (), rs.3.rs-5125826. . PMCID: 11527356.
12.) Anderson BD, Sepulveda DE, Nachnani R, Cortez-Resendiz A, Coates MD, Beckett A, Bisanz JE, Kellogg JJ, Raup-Konsavage WM (2024 Sep). High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model The Journal of Pharmacology and Experimental Therapeutics, 390(3), 331-341. . PMCID: 11338277.
13.) Tian Y, Rimal B, Bisanz JE, Gui W, Wolfe TM, Koo I, Murray IA, Nettleford SK, Yokoyama S, Dong F, Koshkin S, Prabhu KS, Turnbaugh PJ, Walk ST, Perdew GH, Patterson AD (2024 Aug 14). Effects of Early Life Exposures to the Aryl Hydrocarbon Receptor Ligand TCDF on Gut Microbiota and Host Metabolic Homeostasis in C57BL/6J Mice Environmental Health Perspectives, 132(8), 087005. . PMCID: 11323762.
14.) Vue Z, Murphy A, Le H, Neikirk K, Garza-Lopez E, Marshall AG, Mungai M, Jenkins B, Vang L, Beasley HK, Ezedimma M, Manus S, Whiteside A, Forni MF, Harris C, Crabtree A, Albritton CF, Jamison S, Demirci M, Prasad P, Oliver A, Actkins KV, Shao J, Zaganjor E, Scudese E, Rodriguez B, Koh A, Rabago I, Moore JE, Nguyen D, Aftab M, Kirk B, Li Y, Wandira N, Ahmad T, Saleem M, Kadam A, Katti P, Koh HJ, Evans C, Koo YD, Wang E, Smith Q, Tomar D, Williams CR, Sweetwyne MT, Quintana AM, Phillips MA, Hubert (2024 Jul 3). MICOS Complex Loss Governs Age-Associated Murine Mitochondrial Architecture and Metabolism in the Liver, While Sam50 Dictates Diet Changes bioRxiv, (), 2024.06.20.599846. . PMCID: 11230271.
15.) Vue Z, Prasad P, Le H, Neikirk K, Harris C, Garza-Lopez E, Wang E, Murphy A, Jenkins B, Vang L, Scudese E, Shao B, Kadam A, Shao J, Marshall AG, Crabtree A, Kirk B, Koh A, Wilson G, Oliver A, Rodman T, Kabugi K, Koh HJ, Smith Q, Zaganjor E, Wanjalla CN, Dash C, Evans C, Phillips MA, Hubert D, Ajijola O, Whiteside A, Do Koo Y, Kinder A, Demirci M, Albritton CF, Wandira N, Jamison S, Ahmed T, Saleem M, Tomar D, Williams CR, Sweetwyne MT, Murray SA, Cooper A, Kirabo A, Jadiya P, Quintana A, Katti P (2024 Jun 12). The MICOS Complex Regulates Mitochondrial Structure and Oxidative Stress During Age-Dependent Structural Deficits in the Kidney bioRxiv, (), 2024.06.09.598108. . PMCID: 11195114.
16.) Zhu B, Zhu X, Borland MG, Ralph DH, Chiaro CR, Krausz KW, Ntambi JM, Glick AB, Patterson AD, Perdew GH, Gonzalez FJ, Peters JM (2024 May 21). Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) in Keratinocytes by Endogenous Fatty Acids Biomolecules, 14(6), 606. . PMCID: 11201440.
Core for conducting metabolomics studies on variety of biofluids and tissue extracts from plant and animal sources. Provided instruments include Agilent 5975C series GC-MSD, Bruker NEO 600 NMR, Thermo Exactive Plus, Thermo Orbitrap Exploris 120, Thermo Orbitrap Exploris 240, Thermo TSQ Quantis Plus, Thermo Orbitrap Fusion Lumos Tribrid.
