Fred Hutch Cancer Center

Contact Info:

Shared Resources Administration

1201 Eastlake Ave. E.

S5-153

Seattle, WA 98109

https://www.fredhutch.org/en/research/shared-resources/core-facilities/immune-monitoring.html

Grants and Identifiers:

RRID: RRID:SCR_022615

P30CA015704

Instrumentation:

Services Provided:

Cytokine Assays

Immune Monitoring

Tetramer Production

Relevant Publications:

1.) Zhang S, Tang TH, Kinsella S, Mazziotta F, Schweizer MT, McAfee MS, Munkhbat A, Su Y, Voillet V, Martin LE, Smith CW, Asano Y, Hailemariam M, Bakhtiari J, Lee B, Yeung C, Chen H, Rizzi AM, Chen DG, Furiya K, Horst N, Zhang T, Le P, McKenna K, Oda SK, Rongvaux A, Greenberg PD, Schmitt TM, Chapuis AG (2026 Jan 3). A CD8αβ co-receptor modified to contain an intracellular CD28 signaling tail enhances TCR-engineered T cell function independent of solid-tumor-associated co-stimulatory ligands. Nature communications, 17(1), 753. . PMCID: 12820041.

2.) Maynard LH, Cavanaugh EJ, Zhu H, Starke CE, Doherty SM, Einhaus T, Pérez-Osorio AC, Stensland L, Blair C, Roche AM, Everett JK, Murnane RD, Hoffman M, Nelson V, Herrin S, Littlewood C, Camou K, Wilson E, Wessel C, Bushman FD, Jerome KR, Kiem HP, Peterson CW (2025 Nov 20). Pooled CAR-T screening in pig-tailed macaques identifies designs with enhanced proliferation, trafficking, and persistence. Blood, 146(21), 2531-2543. . PMCID: 12809228.

Description:

The Immune Monitoring shared resource supports investigators seeking precise evaluations of immunologic responses in both basic and early-stage clinical research settings. We provide users with resources and expertise to evaluate cellular immunologic processes and responses through reagents, molecular and cellular assays, assay development support and research-consulting services