Fred Hutch Cancer Center
Shared Resources Administration
1100 Eastlake Ave E.
E1-410
Seattle, WA 98109
https://www.fredhutch.org/en/research/shared-resources/core-facilities/antibody-technology.html
RRID: RRID:SCR_022608
Other Citation IdentifiersP30CA015704
Antibody Characterization
Antibody Development
Antibody Production
1.) Scharffenberger SC, Wan YH, Homad LJ, Kher G, Haynes AM, Poudel B, Sinha IR, Aldridge N, Pai A, Bibby M, Chhan CB, Davis AR, Moodie Z, Palacio MB, Escolano A, McElrath MJ, Boonyaratanakornkit J, Pancera M, McGuire AT (2024 Oct 22). Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies. Cell reports, 43(10), 114811. . PMID: 39383036.
2.) Whiteaker JR, Zhao L, Schoenherr RM, Huang D, Kennedy JJ, Ivey RG, Lin C, Lorentzen TD, Colantonio S, Caceres TW, Roberts RR, Knotts JG, Reading JJ, Perry CD, Garcia-Buntley SS, Bocik W, Hewitt SM, Paulovich AG (2024 Jun 25). Characterization of an expanded set of assays for immunomodulatory proteins using targeted mass spectrometry Scientific Data, 11(), 682. . PMCID: 11199596.
3.) Belmont L, Contreras M, Cartwright-Acar CH, Marceau CD, Agrawal A, Levoir LM, Lubow J, Goo L (2024 Apr 27). Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection bioRxiv, (), 2024.04.26.591029. . PMCID: 11071485.
4.) Contreras M, Stuart JB, Levoir LM, Belmont L, Goo L (2024 Jan 9). Defining the impact of flavivirus envelope protein glycosylation site mutations on sensitivity to broadly neutralizing antibodies mBio, 15(2), e03048-23. . PMCID: 10865826.
5.) Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Duran V, Rebellon-Sanchez DE, Sanz AM, Rosso F, Doranz BJ, Einav S, Matsen IV FA, Goo L (2023 Oct 9). Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses PLOS Pathogens, 19(10), e1011722. . PMCID: 10586629.
6.) Kikawa C, Cartwright-Acar CH, Stuart JB, Contreras M, Levoir LM, Evans MJ, Bloom JD, Goo L (2023 Sep 26). The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies bioRxiv, (), 2023.09.13.557606. . PMCID: 10557620.
7.) Davidson KA, Nakamura M, Verboon JM, Parkhurst SM (2023 May 10). Centralspindlin proteins Pavarotti and Tumbleweed along with WASH regulate nuclear envelope budding The Journal of Cell Biology, 222(8), e202211074. . PMCID: 10174194.
Since our inception in 1995, Fred Hutch’s Antibody Technology shared resource has worked with research teams inside and outside the Hutch to design campaign strategies for the generation and identification of novel monoclonal antibody compositions. Our projects encompass a range of applications in oncology, viral therapeutics and diagnostics.
