Fred Hutch Cancer Center
Shared Resources Administration
1100 Fairview Ave N
DE-740
Seattle, WA 98109
https://www.fredhutch.org/en/research/shared-resources/core-facilities/genomics-bioinformatics.html
RRID: RRID:SCR_022606
Other Citation Identifiers P30CA015704
Applied Biosystems 3730xl Capillary Genetic Sequencer
The Applied Biosystems 3730xl is a 96-capillary DNA Analyzer that performs DNA fragment analysis applications such as microsatellites, AFLP, SNP analysis, mutation detection and traditional DNA sequencing. Get the highest quality data at a low cost per sample. Higher optical sensitivity and advanced polymers enable you to obtain higher-quality sequencing data for less. Multiple automation features decrease costly human errors. Optimized polymers increase your productivity without compromising your results. Perform a wide variety of sequencing and fragment analysis applications including resequencing, microsatellite analysis, AFLP, LOH, SSCP, SNP screening and SNP validation. [Product Link]
RRID:SCR_018059
Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
RRID:SCR_020134
Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems
Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]
RRID:SCR_020140
Illumina NovaSeq 6000 Sequencing System
Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]
RRID:SCR_020150
Nanostring nCounter
Nanostring GeoMx
Pacific Biosciences Sequel IIe
10x Genomics Chromium
10x Genomics Visium
Quantstudio
10x Genomics
ATAC-Seq
Automated Liquid Handling
ChIP-Seq
CITE-seq
Computational - Bioinformatics
Consultation
Copy Number Variation (CNV)
CRISPR
Data Analysis
Genome/Transcriptome Assembly And Annotation
Genomics
Genotyping
Genotyping-by-sequencing
High-throughput Screening
Long Read Sequencing
Metagenomics Analysis
Methylation Analysis
Nanostring
NanoString GeoMx DSP
Nanostring NCounter
Real-time qPCR
Sequencing - Capillary Sequencing
Sequencing - DNA Sequencing
Sequencing - Next Generation Sequencing (NGS)
Spatial Transcriptomics
Whole Exome Sequencing
Whole Genome Amplification (WGA)
Whole Genome Sequencing
1.) Avanessian SC, van den Bijgaart RJ, Chew NW, Supper VM, Tang TT, Zhang Y, Zhao YQ, Abe K, Gauthier J, Barry KC (2025 Oct 13). IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy Cancer immunology research, (), 10.1158/2326-6066.CIR-24-1259. . PMCID: 12582536.
2.) Kuhlmann AS, Madkhali N, Moskovitz E, Parrott JE, Raman SS, Riker AO, Martinez-Reyes J, Gupta M, Jang RA, Nelson V, Gray MD, Taylor JJ, Peterson CW, Kiem HP (2025 Sep 22). Heavy-chain immunoglobulin locus editing in rhesus macaque B cells to confer antibody production Molecular Therapy. Methods & Clinical Development, 33(4), 101598. . PMCID: 12554106.
3.) Kikawa C, Huddleston J, Loes AN, Turner SA, Lee J, Barr IG, Cowling BJ, Englund JA, Greninger AL, Harvey R, Hasegawa H, Ho F, Lacombe K, Leung NH, Lewis NS, Peck H, Watanabe S, Smith DJ, Bedford T, Bloom JD (2025 Sep 6). Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025 bioRxiv, (), 2025.09.06.674661. . PMCID: 12425000.
4.) Romero EV, Clyde AE, Giorgi EE, Westfall DH, Azam W, Taylor ML, Caskey M, Feder AF, Cohn LB (2025 Aug 30). Distinct modes of evolution drive HIV escape from two broadly neutralizing antibodies bioRxiv, (), 2025.08.29.673185. . PMCID: 12407991.
5.) Ju X, Hannon WW, Kaszuba T, Radford CE, Larsen BB, Nelson SS, Nelson CA, Baltazar-Perez I, Zimmerman O, Fremont DH, Diamond MS, Bloom JD (2025 Aug 25). Determinants of human versus mosquito cell entry by the Chikungunya virus envelope proteins bioRxiv, (), 2025.08.25.672233. . PMCID: 12407778.
6.) Dadonaite B, Harari S, Larsen BB, Kampman L, Harteloo A, Elias-Warren A, Chu HY, Bloom JD (2025 Aug 19). Spike mutations that affect the function and antigenicity of recent KP.3.1.1-like SARS-CoV-2 variants bioRxiv, (), 2025.08.18.671001. . PMCID: 12393327.
7.) Choo S, Tong AH, Fields E, Mack HM, Humbert O, Radtke S, Kiem HP (2025 Jul 17). A rescue fanconi anemia humanized mouse model with endogenous FA mutation and high human hematopoietic stem cell chimerism Molecular Therapy. Methods & Clinical Development, 33(3), 101528. . PMCID: 12355547.
8.) Farrell-Sherman A, de la Force N, Prator CA, Valieris R, Azam W, Da Silva I, Deeks SG, Thanh C, Bosch RJ, Henrich TJ, Cohn LB (2025 Jul 9). Antiviral Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia The Journal of Infectious Diseases, 232(5), 1061-1066. . PMCID: 12614978.
9.) Paatela EM, St. Amant FG, Hamm DC, Bennett SR, Gujral TS, van der Maarel SM, Tapscott SJ (2025 Jul 8). A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing Human Molecular Genetics, 34(18), 1526-1540. . PMCID: 12409625.
10.) Figueiredo JC, Redwood D, Li L, Donato E, Fort D, Fox EE, Grady WM, Green H, Harrison TA, Haupt C, Hsu L, Hullar MA, Huyghe JR, Johnson W, Koehne AL, LaBrie SD, Lakey MA, Lin M, Loroña NC, Maresh GA, Matrana M, Mizrahi JD, Nash SH, Nguyen NT, Paruch JL, Phipps AI, Qu C, Randolph TW, Romo S, Thomas CE, Thomas S, Tiesinga J, Whitlow C, Yeung CC, Yin H, Zibilich CM, Li CI, Thomas TK, Peters U (2025 Jun 27). The Translational Research Program in Cancer Differences across Populations Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, (), 10.1158/1055-9965.EPI-24-1711. . PMCID: 12349377.
11.) Raychaudhuri S, Gem H, Chung K, McLean JS, Kerns KA, Hullar MA, Elmorr E, Appelbaum JB, Percival ME, Walter RB, Halpern AB, Minot SS, Kim K, Zevin AS, Rashidi A (2025 May 26). Distal gut colonization by oral bacteria during intensive chemotherapy: direct evidence from strain-level analysis of paired samples NPJ Biofilms and Microbiomes, 11(), 88. . PMCID: 12106833.
12.) Landazuri Vinueza J, Salisbury NJ, Dye KN, Roman A, Galloway DA (2025 May 23). Delta-catenin is required for cell proliferation in virus-positive Merkel cell carcinoma cell lines but not in human fibroblasts mBio, 16(6), e00832-25. . PMCID: 12153310.
13.) Alavattam KG, Dickson BM, Hirano R, Dell R, Tsukiyama T (2025 May 5). ChIP-seq Data Processing and Relative and Quantitative Signal Normalization for Saccharomyces cerevisiae Bio-protocol, 15(9), e5299. . PMCID: 12067309.
14.) Vinueza JL, Salisbury NJ, Dye KN, Roman A, Galloway DA (2025 Mar 14). Delta-catenin is required for cell proliferation in virus positive Merkel cell carcinoma cell lines but not in human fibroblasts bioRxiv, (), 2025.03.12.642815. . PMCID: 11952379.
15.) Kikawa C, Loes AN, Huddleston J, Figgins MD, Steinberg P, Griffiths T, Drapeau EM, Peck H, Barr IG, Englund JA, Hensley SE, Bedford T, Bloom JD (2025 Mar 12). High-throughput neutralization measurements correlate strongly with evolutionary success of human influenza strains bioRxiv, (), 2025.03.04.641544. . PMCID: 11952370.
16.) Petty NE, Radtke S, Kanestrom G, Fields E, Humbert O, Fiorenza S, Llewellyn MJ, Laszlo GS, Thomas J, Burger Z, Swing K, Zhu H, Jerome KR, Turtle CJ, Walter RB, Kiem HP (2025 Feb 12). Protection of CD33-modified hematopoietic stem cell progeny from CD33-directed CAR T cells in rhesus macaques Blood Advances, 9(10), 2367-2378. . PMCID: 12141896.
17.) Radford CE, Bloom JD (2025 Jan 30). Comprehensive maps of escape mutations from antibodies 10-1074 and 3BNC117 for Envs from two divergent HIV strains bioRxiv, (), 2025.01.30.635715. . PMCID: 11838258.
18.) Jochim BE, Topalidou I, Lehrbach NJ (2025 Jan 29). Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2 bioRxiv, (), 2025.01.29.635299. . PMCID: 11838306.
19.) Dadonaite B, Burrell AR, Logue J, Chu HY, Payne DC, Haslam DB, Staat MA, Bloom JD (2025 Jan 20). SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals bioRxiv, (), 2025.01.17.633612. . PMCID: 11785066.
20.) Farrell-Sherman A, de la Force N, Prator C, Valieris R, Azam W, Da Silva I, Deeks SG, Thanh C, Bosch R, Henrich TJ, Cohn L (2024 Dec 25). Inflammatory Monocytes Increase Prior to Detectable HIV-1 Rebound Viremia bioRxiv, (), 2024.12.24.630257. . PMCID: 11703239.
21.) Li D, Geng K, Hao Y, Gu J, Kumar S, Olson AT, Kuismi CC, Kim HM, Pan Y, Sherman F, Williams AM, Li Y, Li F, Chen T, Thakurdin C, Ranieri M, Meynardie M, Levin DS, Stephens J, Chafitz A, Chen J, Donald-Paladino MS, Powell JM, Zhang ZY, Chen W, Ploszaj M, Han H, Gu SS, Zhang T, Hu B, Nacev BA, Kaiza ME, Berger AH, Wang X, Li J, Sun X, Liu Y, Zhang X, Bruno TC, Gray NS, Nabet B, Wong KK, Zhang H (2024 Dec 24). Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models The Journal of Clinical Investigation, 135(2), e174249. . PMCID: 11735103.
22.) Aditham AK, Radford CE, Carr CR, Jasti N, King NP, Bloom JD (2024 Dec 17). Deep mutational scanning of rabies glycoprotein defines mutational constraint and antibody-escape mutations. bioRxiv : the preprint server for biology, (), . . PMID: 39763725.
23.) Cucinotta C, Dell R, Alavattam K, Tsukiyama T (2024 Dec 12). Sir2 is required for the quiescence-specific condensed three-dimensional chromatin structure of rDNA bioRxiv, (), 2024.12.12.628092. . PMCID: 11661206.
24.) Barros G, Federico E, Fillingham P, Chanana P, Kaneko N, Zheng Y, Kim LJ, Levitt MR (2024 Dec). Endothelial Cell Transcription Modulation in Cerebral Aneurysms After Endovascular Flow Diversion. Annals of biomedical engineering, 52(12), 3253-3263. . PMID: 39095638.
25.) Paik J, Kim A, Fogassy K, Snyder JM, Brabb T, Dill-McFarland KA, He Q, Amory JK (2024 Nov 11). Weight loss and metabolic effects of an ALDH1A1-specific inhibitor, FSI-TN42, in a diet induced mouse model of obesity. International journal of obesity (2005), (), . doi: 10.1038/s41366-024-01676-3. PMID: 39528599.
26.) Rashidi A, Liang L, Gooley T, Hujoel PP, Zevin A, Rothen M, Hagstrom MK, Cutler C, Lee SJ, Dean DR, Sroussi HY, Treister NS (2024 Nov 1). Microbiota signature of oral chronic graft-versus -host disease 6+ years after transplantation. Haematologica, 109(11), 3800-3805. . PMID: 38988271.
27.) Scharffenberger SC, Wan YH, Homad LJ, Kher G, Haynes AM, Poudel B, Sinha IR, Aldridge N, Pai A, Bibby M, Chhan CB, Davis AR, Moodie Z, Palacio MB, Escolano A, McElrath MJ, Boonyaratanakornkit J, Pancera M, McGuire AT (2024 Oct 22). Targeting RSV-neutralizing B cell receptors with anti-idiotypic antibodies. Cell reports, 43(10), 114811. . PMID: 39383036.
28.) Rashidi A, Pidala J, Hamilton BK, Pavletic SZ, Kim K, Zevin A, Mays JW, Lee SJ (2024 Sep 13). Oral and gut microbiome alterations in oral chronic graft-versus-host disease: results from Close Assessment and Testing for Chronic GVHD (CATCH study) Clinical cancer research : an official journal of the American Association for Cancer Research, 30(18), 4240-4250. . PMCID: 11398982.
29.) Carr CR, Crawford KHD, Murphy M, Galloway JG, Haddox HK, Matsen FA 4th, Andersen KG, King NP, Bloom JD (2024 Sep 10). Deep mutational scanning reveals functional constraints and antibody-escape potential of Lassa virus glycoprotein complex. Immunity, 57(9), 2061-2076.e11. . PMID: 39013466.
30.) Gray CN, Ashokkumar M, Janssens DH, Kirchherr J, Allard B, Hsieh E, Hafer TL, Archin NM, Browne EP, Emerman M (2024 Sep 3). Integrator complex subunit 12 knockout overcomes a transcriptional block to HIV latency reversal bioRxiv, (), 2024.08.30.610517. . PMCID: 11383676.
31.) Moorthi S, Paguirigan A, Itagi P, Ko M, Pettinger M, Hoge AC, Nag A, Patel NA, Wu F, Sather C, Levine KM, Fitzgibbon MP, Thorner AR, Anderson GL, Ha G, Berger AH (2024 Jul 25). The genomic landscape of lung cancer in never-smokers from the Women’s Health Initiative JCI Insight, 9(17), e174643. . PMCID: 11385083.
32.) Rashidi A, Liang L, Gooley T, Hujoel PP, Zevin A, Rothen M, Hagstrom MK, Cutler C, Lee SJ, Dean DR, Sroussi HY, Treister NS (2024 Jul 11). Microbiota signature of oral chronic graft-versus-host disease 6+ years after transplantation Haematologica, 109(11), 3800-3805. . PMCID: 11532723.
33.) Dadonaite B, Brown J, McMahon TE, Farrell AG, Figgins MD, Asarnow D, Stewart C, Lee J, Logue J, Bedford T, Murrell B, Chu HY, Veesler D, Bloom JD (2024 Jul 3). Spike deep mutational scanning helps predict success of SARS-CoV-2 clades Nature, 631(8021), 617-626. . PMCID: 11254757.
34.) Salisbury NJ, Amonkar S, Vinueza JL, Carter JJ, Roman A, Galloway DA (2024 May 25). Polyomavirus ALTOs, but not MTs, downregulate viral early gene expression by activating the NF-κB pathway bioRxiv, (), 2024.05.24.595774. . PMCID: 11142227.
35.) Thirimanne HN, Almiron-Bonnin D, Nuechterlein N, Arora S, Jensen M, Parada CA, Qiu C, Szulzewsky F, English CW, Chen WC, Sievers P, Nassiri F, Wang JZ, Klisch TJ, Aldape KD, Patel AJ, Cimino PJ, Zadeh G, Sahm F, Raleigh DR, Shendure J, Ferreira M, Holland EC (2024 May 23). Meningioma transcriptomic landscape demonstrates novel subtypes with regional associated biology and patient outcome Cell Genomics, 4(6), 100566. . PMCID: 11228955.
36.) Belmont L, Contreras M, Cartwright-Acar CH, Marceau CD, Agrawal A, Levoir LM, Lubow J, Goo L (2024 Apr 27). Functional genomics screens reveal a role for TBC1D24 and SV2B in antibody-dependent enhancement of dengue virus infection bioRxiv, (), 2024.04.26.591029. . PMCID: 11071485.
37.) Larsen BB, McMahon T, Brown JT, Wang Z, Radford CE, Crowe JE Jr, Veesler D, Bloom JD (2024 Apr 19). Functional and antigenic landscape of the Nipah virus receptor binding protein bioRxiv, (), 2024.04.17.589977. . PMCID: 11042328.
38.) Hickson SE, Hyde JL (2024 Apr 9). RNA structures within Venezuelan equine encephalitis virus E1 alter macrophage replication fitness and contribute to viral emergence bioRxiv, (), 2024.04.09.588743. . PMCID: 11030350.
39.) Loes AN, Tarabi RA, Huddleston J, Touyon L, Wong SS, Cheng SM, Leung NH, Hannon WW, Bedford T, Cobey S, Cowling BJ, Bloom JD (2024 Mar 9). High-throughput sequencing-based neutralization assay reveals how repeated vaccinations impact titers to recent human H1N1 influenza strains bioRxiv, (), 2024.03.08.584176. . PMCID: 10942427.
40.) Carr CR, Crawford KH, Murphy M, Galloway JG, Haddox HK, Matsen FA IV, Andersen KG, King NP, Bloom JD (2024 Feb 6). Deep mutational scanning reveals functional constraints and antigenic variability of Lassa virus glycoprotein complex bioRxiv, (), 2024.02.05.579020. . PMCID: 10871245.
41.) Russell ML, Fish CS, Drescher S, Cassidy NA, Chanana P, Benki-Nugent S, Slyker J, Mbori-Ngacha D, Bosire R, Richardson B, Wamalwa D, Maleche-Obimbo E, Overbaugh J, John-Stewart G, Matsen FA IV, Lehman DA (2023 Dec 20). Using viral sequence diversity to estimate time of HIV infection in infants PLOS Pathogens, 19(12), e1011861. . PMCID: 10732395.
42.) Welsh FC, Eguia RT, Lee JM, Haddox HK, Galloway J, Chau NV, Loes AN, Huddleston J, Yu TC, Le MQ, Nhat NT, Thanh NT, Greninger AL, Chu HY, Englund JA, Bedford T, Matsen FA IV, Boni MF, Bloom JD (2023 Dec 12). Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin bioRxiv, (), 2023.12.12.571235. . PMCID: 10760046.
43.) Dadonaite B, Brown J, McMahon TE, Farrell AG, Asarnow D, Stewart C, Logue J, Murrell B, Chu HY, Veesler D, Bloom JD (2023 Nov 14). Full-spike deep mutational scanning helps predict the evolutionary success of SARS-CoV-2 clades bioRxiv, (), 2023.11.13.566961. . PMCID: 10680755.
44.) Lubow J, Levoir LM, Ralph DK, Belmont L, Contreras M, Cartwright-Acar CH, Kikawa C, Kannan S, Davidson E, Duran V, Rebellon-Sanchez DE, Sanz AM, Rosso F, Doranz BJ, Einav S, Matsen IV FA, Goo L (2023 Oct 9). Single B cell transcriptomics identifies multiple isotypes of broadly neutralizing antibodies against flaviviruses PLOS Pathogens, 19(10), e1011722. . PMCID: 10586629.
45.) Kikawa C, Cartwright-Acar CH, Stuart JB, Contreras M, Levoir LM, Evans MJ, Bloom JD, Goo L (2023 Sep 26). The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies bioRxiv, (), 2023.09.13.557606. . PMCID: 10557620.
46.) Hamm DC, Paatela EM, Bennett SR, Wong CJ, Campbell AE, Wladyka CL, Smith AA, Jagannathan S, Hsieh AC, Tapscott SJ (2023 Sep 25). The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced mRNAs PLOS Biology, 21(9), e3002317. . PMCID: 10553841.
47.) Bacsik DJ, Dadonaite B, Butler A, Greaney AJ, Heaton NS, Bloom JD (2023 Sep 7). Influenza virus transcription and progeny production are poorly correlated in single cells. eLife, 12(), . . PMID: 37675839.
48.) Hafer TL, Felton A, Delgado Y, Srinivasan H, Emerman M (2023 Aug 31). A CRISPR Screen of HIV Dependency Factors Reveals That CCNT1 Is Non-Essential in T Cells but Required for HIV-1 Reactivation from Latency Viruses, 15(9), 1863. . PMCID: 10535513.
49.) Sather CL, Yang P, Zhang C, Fitzgibbon MP, Fournier M, Toloza E, Tandon A, Schabath M, Yoder S, Nair VS (2023 Aug 17). Protocol optimization of a targeted sequencing panel for genomic profiling of bronchoalveolar lavage fluid in lung cancer Cancer Medicine, 12(17), 17632-17637. . PMCID: 10524020.
50.) Williams MD, Chen AT, Stone MR, Guo L, Belmont BJ, Turk R, Bogard N, Kearns N, Young M, Daines B, Darnell M (2023 Aug 5). TRAFfic signals: High-throughput CAR discovery in NK cells reveals novel TRAF-binding endodomains that drive enhanced persistence and cytotoxicity. bioRxiv : the preprint server for biology, (), . . PMID: 37577560.
51.) Haddox HK, Galloway JG, Dadonaite B, Bloom JD, Matsen IV FA, DeWitt WS (2023 Aug 2). Jointly modeling deep mutational scans identifies shifted mutational effects among SARS-CoV-2 spike homologs bioRxiv, (), 2023.07.31.551037. . PMCID: 10418112.
52.) Gatbonton-Schwager T, Yagishita Y, Joshi T, Wakabayashi N, Srinivasan H, Suzuki T, Yamamoto M, Kensler TW (2023 Aug). A Point Mutation at C151 of Keap1 of Mice Abrogates NRF2 Signaling, Cytoprotection in Vitro, and Hepatoprotection in Vivo by Bardoxolone Methyl (CDDO-Me) Molecular Pharmacology, 104(2), 51-61. . PMCID: 10353147.
53.) Hafer TL, Felton A, Delgado Y, Srinivasan H, Emerman M (2023 Jul 28). A CRISPR screen of HIV dependency factors reveals CCNT1 is non-essential in T cells but required for HIV-1 reactivation from latency bioRxiv, (), 2023.07.28.551016. . PMCID: 10402164.
54.) Garcia NM, Becerra JN, McKinney BJ, DiMarco AV, Wu F, Fitzgibbon M, Alvarez JV (2023 Jul 3). APOBEC3 activity promotes the survival and evolution of drug-tolerant persister cells during acquired resistance to EGFR inhibitors in lung cancer bioRxiv, (), 2023.07.02.547443. . PMCID: 10350004.
55.) Twentyman J, Khalifeh A, Felton AL, Emerman M, OhAinle M (2023 Mar 25). Primate TRIM34 is a broadly-acting, TRIM5-dependent lentiviral restriction factor bioRxiv, (), 2023.03.24.534139. . PMCID: 10055373.
56.) Radford CE, Schommers P, Gieselmann L, Crawford KH, Dadonaite B, Yu TC, Dingens AS, Overbaugh J, Klein F, Bloom JD (2023 Mar 24). Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning bioRxiv, (), 2023.03.23.533993. . PMCID: 10055425.
57.) Montoya VR, Ready TM, Felton A, Fine SR, OhAinle M, Emerman M (2023 Feb 6). A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains mBio, 14(1), e00009-23. . PMCID: 9973025.
58.) Hsieh E, Janssens DH, Paddison PJ, Browne EP, Henikoff S, OhAinle M, Emerman M (2023 Jan 27). A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency PLOS Pathogens, 19(1), e1011101. . PMCID: 9907829.
59.) Moorthi S, Paguirigan A, Ko M, Pettinger M, Hoge ACH, Nag A, Patel NA, Wu F, Sather C, Fitzgibbon MP, Thorner AR, Anderson GL, Ha G, Berger AH (2023 Jan 6). Somatic mutation but not aneuploidy differentiates lung cancer in never-smokers and smokers. bioRxiv : the preprint server for biology, (), . . PMID: 36712079.
The Genomics & Bioinformatics shared resource provides an integrated, streamlined and expertly supported set of services that encompass experimental design, data generation and data interpretation. Expert genomics and bioinformatics teams are available to consult and collaborate at every step of the process and work closely together to develop optimized experimental strategies to ensure that appropriate technology and data analysis tools are used to address each unique scientific question.
