IFOM's Functional Genomics Screening (FGS) Core Facility specializes in high-throughput CRISPR screening using pooled or arrayed libraries in diverse cellular models. This technology assesses the effects of thousands of genetic perturbations at single-cell resolution with CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa). It also utilizes base and prime editing to investigate specific mutations, such as those relevant to cancer development and progression. 

IFOM's Flow Cytometry (FC) Core Facility provides cutting-edge technology, state-of-the-art instrumentation, and expert support for a wide range of applications, including:
• Immunophenotyping
• Cell cycle and proliferation analysis
• Metabolic studies
• Apoptosis detection
• Fluorescent protein expression analysis
• Cytokine, chemokine, and intra/extracellular protein detection

IFOM's Advanced Light Microscopy (ALM) Core Facility provides state-of-the-art technological platforms in the field of light microscopy. A team of highly qualified and experienced professionals with diverse scientific backgrounds supports IFOM's research activities, assisting not only in sample preparation and acquisition but also in data post-processing and image analysis.

IFOM's Cancer Engineering R&D (CERD) Core Facility focuses on the development of innovative biomedical technologies/devices for cancer research as well as biomedical applications using microfabrication and 3D printing. 

IFOM's Electron Microscopy Cells & Tissues (EMCT) CoreFacility performs not only routine transmission and scanning EM, but also all kinds of immune EM, correlative light electron microscopy (CLEM), three-dimensional EM (3DEM), quantitative stereological evaluation of data and so on.

IFOM's Electron Microscopy Single Molecues (EMSM) Core Facility uses transmission electron microscopy coupled to low angle rotary shadowing to visualize nucleic acids. This technique allows the inspection of the fine ultrastructure of in vivo chromosomal DNA intermediates on properly enriched genomic DNA samples. 

IFOM's Cellular and Preclinical Models (CPM) Core Facility is a specialized laboratory environment designed for the growth, maintenance, and experimentation of living cells under controlled conditions. This facility is used in various fields such as biomedical research, drug development, and supports the culture of primary cells, immortalized cell lines, human-induced pluripotent stem cells (hiPSCs), and organoids, among others.