TOPS is a UPMC Hillman Cancer Center managed and regulated resource that provides coordinated collection, processing, annotation, distribution, and storage of patient biospecimens to investigators and their respective collaborators.  

The UPMC Hillman Cancer Center In Vivo Imaging Facility provides novel quantitative imaging techniques that trace biomarkers of molecular events associated with effective cancer therapy.

The Immunologic Monitoring and Cellular Products Laboratory at UPMC Hillman Cancer Center operates 12 clean rooms and focuses on IND manufacturing under cGMP/cGTP. Operations are monitored 24/7 by expert staff. The facility specializes in and collaborates on preclinical research development involving process conceptualization, technology transfer and testing implementation on human cell-based drugs for clinical trials. Immunological monitoring services are available to support clinical trials. The facility is a FACT-, CLIA-, CAP-, and FDA-accredited laboratory.

The UPMC Hillman Cancer Center Cancer Pharmacokinetics and Pharmacodynamics Facility provides accessible, economical, comprehensive, and state-of-the-art bioanalytical, pharmacokinetic and pharmacology research services that support preclinical and clinical research programs focused on oncology at UPMC Hillman Cancer Center and medical institutions nationwide. Resources include HPLC-UV/fluorescence, ICP-MS, LC-MS/MS, LSC, ELISA, and in vivo rodent procedures, as well as advanced PK software suites and expertise for preclinical and clinical projects.

The Cancer Genomics Facility at UPMC Hillman Cancer Center supports genomics and transcriptomics platforms including nucleic acid extraction, sample QC, next-generation library preparation and sequencing. The facility specializes in paraffin-embedded tissue samples.

The Cancer Bioinformatics Services at UPMC Hillman Cancer Center provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies.

The Cytometry Facility at UPMC Hillman Cancer Center supports analytical cytometry and cell sorting. The facility also offers NanoString Digital Spatial Analyzer and nCounter service and support.

The Biostatics Facility at UPMC Hillman Cancer Center provides statistical and computational methods for design, execution, analysis, and reporting of cancer-related research studies and trials including biomarker analysis and grant development.