A wide range of chromosome analysis techniques are available ranging from basic G-banded karyotyping to FISH -based assays.

We do not handle routine clinical diagnostic samples.

The Antibody and Bioresource Core Facility supports researchers at both Memorial Sloan-Kettering Cancer Center and The Rockefeller University by making it easier for them to:


1.) Develop new monoclonal antibodies that meet their experimental needs through any combination of these services:

... Consultation
... Immunization of mice, rats and Armenian hamsters
... Electrofusion (B cell immortalization / generation of 10,000's of hybridoma)
... Isolation of IgG secreting hybridomas, which is 1 - 20% of the hybridomas, for screening to enable a greater number of hybridomas are screened
... ELISA screening
... Cryopreservation and storage of positive cultures
... Subcloning
... Cryopreservation and storage of unscreened fusion products / hybrridomas for future screening


2.) Produce monoclonal antibodies

... Conditioned Media
...... 1 to 10 ug monoclonal antibody / ml

... Bioreactor Supernatants:
...... 0.5 to 4 mg monoclonal antibody / ml
...... Purity ranges from 20 to 80%

... Purified monoclonal antibodies:
...... 1 to 10 mg monoclonal antibody / ml
...... Purity > 95%

... Conjugations

... Fragmentation


3.) Mycoplasma Testing


4.) Obtain cell lines developed at Memorial Sloan Kettering Cancer Center and The Rockefeller University


This facility is designed to be both an informational resource as well as a group that provides services for a fee.

Depending upon internal demand, external requests are welcome.

The aim of the Flow Cytometry Core Facility at MSKCC is to provide advanced instrumentation as well as high-level technical and scientific expertise in multi-dimensional Flow Cytometry and Cell Sorting, to facilitate science, improve the quality, and advance the scope of MSK research.

We are a team of product development professionals who help institutions and their investigators comply with FDA regulations in the development and manufacturing of investigational products (drugs, biologics, devices) for human clinical trials. Our main work areas are:
- writing quality system documents (e.g., SOPs, Master Batch Records)
- writing IND and IDE applications
- GMP and GLP training programs
- project management for product development
- planning non-clinical studies and placing studies at a CRO
- planning manufacturing and testing programs
- monitoring work at CROs and CMOs
- auditing laboratories and records
- QA review of completed batch records, or of study reports
- planning and management of product stability studies

At our home institution, Memorial Sloan Kettering Cancer Center, we write 5 or more IND applications annually and provide QA services for over 40 manufactured products.

We charge for our work time plus expenses.