Offers access to instrumentation, training and services for structure determination of macromolecular molecules using single crystal X-ray diffraction and/or cryo-EM Single Particle Analysis (SPA). Instrumentation is available for initial crystallization trials, optimization of crystallization, single crystal X-ray diffraction and data collection at synchrotron radiation facilities, as well as electron microscopy grid preparation for cryo-EM (SPA), screening and data collection using a Thermo Scientific Tundra Cryo-TEM and assistance for data collection at national laboratories.

Offers access to instrumentation, training, and services for protein expression, purification, and biophysical characterization. In addition to instrument access, PPCC personnel offer advice, hands-on training, education, and collaboration. Provides a range of protein purification and characterization equipment.

The Samuel Roberts Noble Microscopy Laboratory, the core imaging facility of the University of Oklahoma, is a central shared use facility offering access to instrumentation, training, and service using advanced light microscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM).

Our mission is to provide effective and efficient access to core imaging and analytical characterization technologies. We welcome all OU-Norman, OUHSC, and OMRF student, faculty, and staff researchers at our centralized location the OU-Norman main campus. Clients from other universities, foundations and industry are welcome to use this equipment as well, and such work may be done on an invoice or contract basis.

In addition to instrument access, SRNML personnel offer advice, hands-on training, education, and research collaboration. The SRNML aims to promote, enable, and encourage cutting-edge education and research using the core’s instrumentation.

We have a range of sample preparation equipment available; our staff work with users and provide training. Please see our equipment and getting started pages for more information, and don’t hesitate to contact us.