New York University School of Medicine

Contact Info:

Brianna Alvarez

New York, NY 10016

https://med.nyu.edu/research/scientific-cores-shared-resources/proteomics-laboratory

Grants and Identifiers:

RRID: RRID:SCR_017926

Instrumentation:

Other Equipment

comprehensive protein identification analysis of affinity purified complexes characterizing protein post-translational modifications de novo sequencing label and label-free quantitation multiplexed quantitation global phosphorylation and ubiquitin analysis analysis of laser-capture microdissected formalin-fixed paraffin-embedded tissue secretome analysis crosslinking analysis disulfide mapping

Services Provided:

Proteomics

Sequencing - Protein Sequencing

Relevant Publications:

1.) Cheng P, Mermerian-Baghdassarian A, Wang Y, Chen Z, Quysbertf HM, Cheema PS, Mays JC, Zhao X, Katsnelson L, Mei S, Shrivastava R, Bulatovic M, Deng J, Schober M, Wong KK, Davoli T (2026 May 7). PARP1 suppression drives ROS resistance in aneuploid cancer cells. Molecular cell, 86(9), 1742-1761.e19. . PMCID: 13224397.

2.) Cheng P, Mermerian-Baghdassarian A, Wang Y, Chen Z, Quysbertf HM, Cheema PS, Mays JC, Zhao X, Katsnelson L, Mei S, Shrivastava R, Bulatovic M, Deng J, Schober M, Wong KK, Davoli T (2026 Feb 16). PARP1 Suppression Drives ROS Resistance in Aneuploid Cancer Cells. bioRxiv : the preprint server for biology, (), . . PMCID: 12934708.

3.) Coleman KE, Shin DW, Goehring L, Szeitz B, Fenyö D, Rothenberg E, Poirier JT, Huang TT (2025 Dec 10). SLFN11 counteracts the RFWD3-PRIMPOL DNA damage tolerance axis to restrain gapped DNA synthesis in response to replication stress. Nature communications, 16(1), 11029. . PMCID: 12696100.

4.) Wang L, Noyer L, Jishage M, Wang YH, Tao AY, McDermott M, Gando I, Sidhu I, Hu K, Zhong L, Sun K, Drmic D, Kaufmann U, Feske S (2025 Jun 20). CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity. Science immunology, 10(108), eadq8860. . PMID: 40540585.

5.) Zhong L, Wang YH, Kahlfuss S, Jishage M, McDermott M, Yang J, Tao AY, Hu K, Noyer L, Raphael D, Patel D, Knight TE, Chitlur M, Machaca K, Feske S (2025 Mar). STIM1-mediated NFAT signaling synergizes with STAT1 to control T-bet expression and T(H)1 differentiation. Nature immunology, 26(3), 484-496. . PMCID: 12121662.

6.) Gasser MT, Liu A, Altamia M, Brensinger BR, Brewer SL, Flatau R, Hancock ER, Preheim SP, Filone CM, Distel DL (2024 Sep 8). Membrane vesicles can contribute to cellulose degradation by Teredinibacter turnerae, a cultivable intracellular endosymbiont of shipworms. bioRxiv : the preprint server for biology, (), . . PMID: 38585906.

7.) Ulrich RJ, Podkowik M, Tierce R, Irnov I, Putzel G, Samhadaneh N, Lacey KA, Boff D, Morales SM, Makita S, Karagounis TK, Zwack EE, Zhou C, Kim R, Drlica K, Pironti A, van Bakel H, Torres VJ, Shopsin B (2024 Apr 17). Prophage-encoded methyltransferase drives adaptation of community-acquired methicillin-resistant Staphylococcus aureus bioRxiv, (), 2024.04.17.589803. . PMCID: 11042277.

8.) Brady M, Shchepetkina VI, González-Recio I, Martínez-Chantar ML, Buccella D (2023 Oct 11). Ratiometric Fluorescent Sensors Illuminate Cellular Magnesium Imbalance in a Model of Acetaminophen-Induced Liver Injury. Journal of the American Chemical Society, 145(40), 21841-21850. . PMID: 37782839.

9.) Wang YH, Noyer L, Kahlfuss S, Raphael D, Tao AY, Kaufmann U, Zhu J, Mitchell-Flack M, Sidhu I, Zhou F, Vaeth M, Thomas PG, Saunders SP, Stauderman K, Curotto de Lafaille MA, Feske S (2022 Oct 7). Distinct roles of ORAI1 in T cell-mediated allergic airway inflammation and immunity to influenza A virus infection. Science advances, 8(40), eabn6552. . PMID: 36206339.

10.) Cheng P, Zhao X, Katsnelson L, Camacho-Hernandez EM, Mermerian A, Mays JC, Lippman SM, Rosales-Alvarez RE, Moya R, Shwetar J, Grun D, Fenyo D, Davoli T (2022 Sep 21). Proteogenomic analysis of cancer aneuploidy and normal tissues reveals divergent modes of gene regulation across cellular pathways eLife, 11(), e75227. . PMCID: 9491860.

11.) Churchill MJ, du Bois H, Heim TA, Mudianto T, Steele MM, Nolz JC, Lund AW (2022 May 2). Infection-induced lymphatic zippering restricts fluid transport and viral dissemination from skin. The Journal of experimental medicine, 219(5), . . PMID: 35353138.

Description:

NYU School of Medicine’s Proteomics Laboratory offers investigators specialized expertise for the analysis of proteins and peptides using mass spectrometry. Our laboratory continually develops new methods and customized approaches for proteomic analysis and suggests experimental strategies and sample preparation prior to mass spectrometry analysis.