Sanford Burnham Prebys Medical Discovery Institute
Contact Info:
Weiliang Huang, PhD
10901 N Torrey Pines Rd
La Jolla, CA 92037
https://sbpdiscovery.org/research/shared-resources/proteomics/
Grants and Identifiers:
RRID: RRID:SCR_022225
Instrumentation:
EASY-nLC 1200 System
System provides peak performance for nanoflow applications up to 1200 bar. Dual in-line flow sensors before solvent mixing give excellent gradient precision. Its intuitive software facilitates rapid method setup and immediate system control. [Product Link]
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Exactive Plus Orbitrap Mass Spectrometer
Screen, identify and quantify compounds in complex samples rapidly and with confidence using the Thermo Scientific Exactive Plus Orbitrap Mass Spectrometer. This benchtop LC-MS system delivers high-resolution, accurate-mass (HR/AM) data and fast full-scan capabilities to increase your sample throughput and confidence in results. Easy-to-use and cost effective to operate, it is the best instrument for analytical laboratories performing food safety or environmental screening, clinical research, forensic toxicology, DMPK, metabolomics and biopharma (intact protein analysis) applications. [Product Link]
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Orbitrap Fusion Lumos Tribrid Mass Spectrometer
Spectrometer performs analysis including low level PTM analysis, multiplexed relative quantitation using isobaric tags, intact protein characterization, and MSn analysis of small molecules. System incorporates the brightest ion source, segmented quadrupole mass filter with improved selectivity and ion transmission, Advanced Vacuum Technology, and ETD HD. [Product Link]
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Services Provided:
Label Free Quantitative Proteomics
Labeled Quantitative Proteomics -TMT And Other Labeling
Mass Spectrometry - Proteins And Peptides
Protein Interactions (IP/MS, AP/MS, Proximity Labeling, DNA-protein Interactions, Chemoproteomics)
Proteomics Sample Preparation (buffer Exchange, Chromatography, Digestion, Stable Isotope Labeling)
Quantitative Phosphoproteomics
Relevant Publications:
Description:
The Sanford Burnham Prebys Proteomics Shared Resource provides state-of-the-art mass spectrometry-based proteomics services including identification, quantification and characterization of proteins and their post-translational modifications. We provide proteomics services to Institute scientists as well as outside non-profit and for-profits organization on a fee-for-service basis.
