IFOM

Contact Info:

Giuseppina d'Alessandro

Va Adamello 22

Milan

https://www.ifom.eu/en/cancer-research/technological-units/functional-genomics-screening-unit.php

Grants and Identifiers:

RRID: RRID:SCR_026867

Instrumentation:

Services Provided:

Relevant Publications:

Description:

IFOM's Functional Genomics Screening (FGS) Core Facility specializes in high-throughput CRISPR screening using pooled or arrayed libraries in diverse cellular models. This technology assesses the effects of thousands of genetic perturbations at single-cell resolution with CRISPR knockout (CRISPR KO), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa). It also utilizes base and prime editing to investigate specific mutations, such as those relevant to cancer development and progression.