Augusta University

Contact Info:

Martina Zoccheddu

https://www.augusta.edu/cancer/research/shared-resources/genomics/

Grants and Identifiers:

RRID: RRID:SCR_026483

Instrumentation:

Services Provided:

Relevant Publications:

1.) Lu C, Liang L, Wu Y, Yang Y, Poschel D, Zhao Y, Pei L, Yu M, Zoccheddu M, Bombin S, Ding HF, Shi H, Liu K (2025 Oct). Slc7a5 promotes T cell anti-tumor immunity through sustaining cytotoxic T lymphocyte effector function. Oncogene, 44(41), 3939-3954. . PMID: 40858813.

2.) Takezaki M, Li B, Xu H, Patel N, Lucas R, Cerbone RE, Koti S, Hendrick CL, Junker LH, Pace BS (2025). The histone deacetylase inhibitor CT-101 flips the switch to fetal hemoglobin expression in sickle cell disease mice. PloS one, 20(5), e0323550. . PMID: 40359410.

3.) Sreekumar A, Ajith A, Mamouni K, Horuzsko DD, Horuzsko A (2025). TREM1 is essential for maintaining stemness of liver cancer stem-like cells in hepatocellular carcinoma. Frontiers in immunology, 16(), 1618342. . PMID: 40677705.

Description:

Core offers services from sample processing from both fresh and frozen, as well as fixed cells or tissues to library preparation and next-generation sequencing (NGS) for bulk DNA/RNA sequencing and single-cell/nuclei sequencing. For single-cell studies, core is equipped with Chromium X system from 10X Genomics. Sequencing capabilities include Illumina Novaseq6000 and NextSeq 500. Offers single cell spatial transcriptomics with CosMx SMI platform. Other equipped includes CytAssit instrument from 10X genomics for VISIUM spatial transcriptomic and QIAConnect from Qiagen for nucleic acid and protein extraction.