University of Kentucky

Contact Info:

Chris Richards

https://www.research.uky.edu/light-microscopy-core

Grants and Identifiers:

RRID: RRID:SCR_026405

Instrumentation:

Services Provided:

Relevant Publications:

1.) Squarci C, Koch D, Anaya P, Campbell KS, Kampourakis T (2026 Feb 10). Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechanosensing. Proceedings of the National Academy of Sciences of the United States of America, 123(6), e2520471123. . PMCID: 12891028.

2.) Franklin MK, Howatt DA, Moorleghen JJ, Sheppard MB, Sawada H, Lu HS, Daugherty A (2025 Nov 30). Angiotensin II Induces Abdominal Aortic Branch Aneurysms in Fibrillin-1 (C1041G/+) Mice. bioRxiv : the preprint server for biology, (), . . PMID: 41394635.

3.) Jolly JT, Al-Hamaly MA, Smith CN, Spielmann HP, Blackburn JS (2025 May 18). Phosphatase activity is dispensable for PRL-3-mediated oncogenesis and tumor progression bioRxiv, (), 2025.05.14.654016. . PMCID: 12132575.

Description:

Core facility offers fluorescence, confocal, super resolution, multi-photon, laser capture and atomic force microscopy. Provides central preparatory laboratory and high-end computer workstations for data analysis and image processing. Technical support ranges from investigator training on instrumentation, allowing independent use, to complete processing of samples and final imaging by facility staff. The facility is GRP accredited, undergoes annual compliance checks and provides extensive standard operating procedures for all instrumentation.