Virginia Commonwealth University
Contact Info:
Faik Musayev
800 East Leigh Street, Suite 212
Richmond, VA 23219
https://research.vcu.edu/cores/structural-biology/
Grants and Identifiers:
RRID: RRID:SCR_026455
Other Citation Identifiers1S10OD021756-01A1
Instrumentation:
(Equipment No Longer Active At this Facility)
Art Robbins Instrument Rigaku Gryphon Crystallization Robot
(Equipment No Longer Active At this Facility)
Rigaku MicroMax-007HF X-ray Generator with VariMax-HF Arc Optics/Dectris Eiger 4M Detector
Services Provided:
Relevant Publications:
Description:
The Structural Biology Core is a multi-user facility serving both the VCU campus and external research institutes. The core encompasses X-ray crystallography, Cryo-Electron Microscopy (Cryo-EM), and Nuclear Magnetic Resonance (NMR) facilities, and is also closely associated with the School of Pharmacy Molecular Modeling facility. The Structural Biology Core provides access to state-of-the art equipment, offering researchers the capability to determine the 3D structure of macromolecules and macromolecular complexes. This yields a diverse array of information on their biological or physiological functions, and enables structure-based drug design, protein-ligand or DNA binding studies, testing mutational effects on target macromolecules, and finding the absolute stereochemistry of chiral compounds. Additionally, the core offers training, technical support, and collaborative opportunities, which are crucial for structural biologists and other researchers studying the structure of biological macromolecules and other materials.