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ENPRC Genomics Core

Emory University

Contact Info:

Emma Shippee, Technical Director

954 Gatewood Rd NE

NSB 5267

Atlanta, GA 30329

https://enprc.emory.edu/nhp_genomics_core/index.html

Grants and Identifiers:

RRID: RRID:SCR_026418

Other Citation Identifiers

1S10OD026799-01

3P51OD011132-62S2

1S10OD038274-01

Instrumentation:

10X Genomics Chromium X Single Cell Analyzer

Analyzer used for high throughput full range single cell analysis. Chromium X runs high-throughput assays. It runs all single cell assays, including high-throughput assays for Single Cell Immune Profiling and Single Cell Gene Expression. [Product Link]

RRID:SCR_024537

cite this instrument

10x Genomics Visium CytAssist

Compact, benchtop instrument that enables transfer of transcriptomic probes from standard glass slides to Visium slides, enabling spatial profiling insights to be gained from even more samples. Enables whole transcriptomic spatial profiling insights across entire tissue section, and expanded compatibility with FFPE and/or FF samples. [Product Link]

RRID:SCR_024570

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10x Genomics Xenium Analyzer

Xenium Analyzer offers subcellular profiling of 100s to 1,000s of RNA targets alongside multiplexed protein, in fresh, frozen or FFPE tissue. [Product Link]

RRID:SCR_023910

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Agilent 2100 Bioanalyzer Instrument

This Bioanalyzer Instrument is used for sample quality control of biomolecules. [Product Link]

RRID:SCR_019389

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Agilent 4200 TapeStation System

TapeStation System is used to analyze DNA and RNA samples for quality control. [Product Link]

RRID:SCR_019398

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Agilent 5300 Fragment Analyzer System

Fragment Analyzer System can separate up to 48 or 96 samples in parallel. [Product Link]

RRID:SCR_019411

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Agilent Bravo NGS

Built NGS is used to automate your routine genomics workflows including library prep and enrichment. [Product Link]

RRID:SCR_019473

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Illumina MiSeq System

Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]

RRID:SCR_020134

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Illumina NovaSeq 6000 Sequencing System

Unleashes groundbreaking innovations that leverage our technology Now you can get scalable throughput and flexibility for virtually any sequencing method, genome, and scale of project. [Product Link]

RRID:SCR_020150

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Illumina NovaSeq X Plus

NovaSeq X Plus Sequencing System has ability to sequence more than 128 genomes per run. Provides faster run times, and the ability to process data directly on the instrument. Uses dual flow cells. Production scale sequencing system can also perform broad range of data intensive applications, from single-cell analysis to exome and circulating tumor DNA sequencing. [Product Link]

RRID:SCR_024568

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Kingfisher Flex System

Automatic Magnetic Bead Cell Isolation System. Benchtop instrument for the purification and extraction of DNA, RNA, proteins, and cells in laboratory settings. It uses magnetic particle technology to handle medium to high throughput processing of 24 or 96 samples per run, providing a more efficient and consistent alternative to manual methods. [Product Link]

RRID:SCR_027576

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Life Technologies Countess Automated Cell Counter

Automated cell counter that can perform cell counts, viability calculations, hemocytometry, fluorescent protein expression, and measure fluorescence capabilities. There are also reusable slides, fluorescence capabilities, and brightfield fluorescence channels. [Product Link]

RRID:SCR_018591

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Life Technologies QuantStudio 3 Real Time PCR System

Applied Biosystems QuantStudio 3 Real-Time PCR System is designed for users who need an , easy-to-use real-time PCR system that doesn't compromise performance and quality. The simplified Design and Analysis software is best for both first-time and experienced users. When connected to the Thermo Fisher Cloud, the QuantStudio 3 system provides access to your data wherever and whenever you want. Using OptiFlex technology (featuring 4 coupled channels and white LED) and featuring three independent Veriflex temperature zones, the QuantStudio 3 system enables improved data accuracy and sensitivity for a broad range of genomic applications. [Product Link]

RRID:SCR_020238

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Qiagen QIAcube

DNA/RNA Protein Purification System for automated purification of nucleic acids and proteins in molecular biology applications. [Product Link]

RRID:SCR_020414

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(Equipment No Longer Active At this Facility)

10x Genomics Chromium X Controller

(Equipment No Longer Active At this Facility)

10x Genomics Cytassist

(Equipment No Longer Active At this Facility)

10x Genomics Visium CytAssist

(Equipment No Longer Active At this Facility)

Illumina Illumina NovaSeq X Plus Sequencing System

(Equipment No Longer Active At this Facility)

Illumina Novaseq X Plus

Sequencer

(Equipment No Longer Active At this Facility)

Illumina NovaSeq X Plus Sequencing System

(Equipment No Longer Active At this Facility)

LifeTech King Fisher Flex

PacBio Vega

Long Read Sequencer

Services Provided:

10x Genomics

10X Genomics Single Cell

10x Genomics Visium

ATAC-Seq

Bioinformatics Analysis

Consultation

Illumina MiSeq Sequencing

Illumina RNA/DNA NGS Library Construction

Library Services

Long Read Sequencing

MiRNA-Seq

Nucleic Acid Extraction

Real-time QPCR

RNA Analysis

RNA Integrity

RNA Isolation

RNA/DNA Quality Control

RNAseq

Sequencing - Next Generation Sequencing (NGS)

Single Cell ATAC-Seq

Single Cell RNA Sequencing

Single Cell RNAseq

Spatial Transcriptomics

Ultra-Low RNA-Seq

Visium HD Spatial Transcriptomics

Relevant Publications:

1.) Sun X, Kwan JJ, Kothari K, Nazzari AF, Kosters A, Fields CA, Thai BQ, Bhattacharya D, Atkins M, Tung KC, Zhao X, Manchev VT, Kennedy M, Ghosn E, Keller G (2026 May 7). Modeling human B cell development with pluripotent stem cells. bioRxiv : the preprint server for biology, (), . . PMCID: 13174478.


2.) Bair CR, VanInsberghe D, Lowen AC, Conn GL, Neufeldt CJ (2026 Apr 8). Comparative analysis of flavivirus sfRNA dynamics and secondary structure. bioRxiv : the preprint server for biology, (), . . PMCID: 13082053.


3.) Oviedo A, Bair CR, Vasilakopoulos AP, Regis K, Vanlnsberghe D, Lowen AC, Conn GL (2026 Apr 2). Conserved stem-loops of the SARS-CoV-2 5'-UTR activate OAS1. bioRxiv : the preprint server for biology, (), . . PMCID: 13060329.


4.) Lee J, Niavi C, Ahn E, Kissick HT, Valanparambil RM, Nasti TH, McGuire DJ, Hua D, Obeng R, Wolfarth AA, Borgonia D, Ferrando-Martinez S, Choi D, Lee BH, Ahmed R (2026 Mar 31). Expansion and mobilization of virus-specific stem-like CD8 T cells in chronic viral infection after treatment with a long-acting IL-7, NT-I7. Cell reports, 45(4), 117204. . PMCID: 13222646.


5.) Elkins C, Zhang J, Ye C, Moll S, Weitzmann MN, Li C (2026 Feb 9). Context-dependent roles of sex hormone signaling in controlling visceral adipose tissue Treg heterogeneity and clonal expansion. Journal of immunology (Baltimore, Md. : 1950), 215(2), . . PMCID: 12998544.


6.) Peres A, Upadhyay AA, Klein V, Saha S, Rodriguez OL, Vanwinkle ZM, Karunakaran K, Metz A, Lauer W, Lin MC, Melton T, Granholm L, Polak P, Peterson SM, Peterson EJ, Raju N, Shields K, Schultze S, Ton T, Ericsen AJ, Lapp SA, Villinger F, Ohlin M, Cottrell CA, Amara RR, Derdeyn CA, Crotty S, Schief WR, Karlsson Hedestam GB, Smith ML, Lees W, Watson CT, Yaari G, Bosinger SE (2026 Jan 13). Population-level genomic analysis of immunoglobulin loci variation in rhesus macaques reveals extensive germline diversity. Immunity, 59(1), 213-228.e6. doi: 10.1016/j.immuni.2025.12.002. PMID: 41494536.


7.) Salinas TR, Harper J, Deleage C, Nguyen K, Auger J, Flores HR, Wilkes AC, Stammen RL, Wood JS, Tharp GK, Bosinger SE, Cottrell ML, Kose E, Immonen TT, Lifson JD, Laird GM, Keele BF, Jones RB, Badley AD, Silvestri G, Kulpa DA, Paiardini M (2025 Jul 14). BCL-2 Inhibition via Venetoclax at ART Initiation Induces Long-Term Reduction of the Intact SIV Reservoir Research Square, (), rs.3.rs-7060088. . PMCID: 12288516.


Description:

The EPC Genomics Core supports your research projects by assisting in experimental design, sample preparation, library prep and sequencing, and data analysis and bioinformatics. Due to our location at the Emory National Primate Research Center, we have developed extensive experience working with non-human primate genomes and other non-standard genomes in addition to the more commonly studied human and mouse genomes. Our close relationship with the Emory Vaccine Center means that we also have significant expertise in the use of transcriptomics and genomics to study immune responses and repertoires. We own an Illumina NovaSeq 6000 (supported by NIH S10 OD026799) and an Illumina MiSeq (supported by the Emory Center for AIDS Research), allowing us to provide rapid support for a wide range of NGS assays. Our website lists a selection of the more commonly run assays at our core, so if you see something that you would like us to help you with or if you have an assay request that you don‘t see listed here please feel free to contact us.