Montana State University

Contact Info:

Kristen Connolly

366 Barnard Hall

Montana State University

Bozeman, MT 59717

https://biofilmlab.org/

Grants and Identifiers:

RRID: RRID:SCR_026519

Instrumentation:

Services Provided:

Confocal Microscopy

Digital Light Sheet Microscopy

Fluid Imaging

Gel Chromatography

Image Analysis

Optical Coherence Tomography

Raman Spectroscopy

Sequencing - Next Generation Sequencing (NGS)

Spectrophotometry

Widefield Imaging

Relevant Publications:

1.) Ketteler HM, Johnson EL, McGlennen M, Dieser M, Foreman CM, Warnat S (2025 Jun). A simulated microgravity biofilm reactor with integrated microfabricated sensors: Advancing biofilm studies in near-space conditions. Biofilm, 9(), 100263. . ID: 40083859.

2.) Anjum S, Parks K, Clark K, Parker A, Heveran CM, Gerlach R (2025 Jan 27). Strengthening biopolymer adhesives through ureolysis-induced calcium carbonate precipitation. Scientific reports, 15(1), 3453. . ID: 39870653.

3.) Vahidi G, Boone C, Hoffman F, Heveran C (2024 Sep). Aging decreases osteocyte peri-lacunar-canalicular system turnover in female C57BL/6JN mice. Bone, 186(), 117163. . ID: 38857854.

4.) Buckner E, Buckingham-Meyer K, Miller LA, Parker AE, Jones CJ, Goeres DM (2024 Aug). Coupon position does not affect Pseudomonas aeruginosa and Staphylococcus aureus biofilm densities in the CDC biofilm reactor. Journal of microbiological methods, 223(), 106960. doi: 10.1016/j.mimet.2024.106960. ID: 38788980.

5.) Kohtz AJ, Petrosian N, Krukenberg V, Jay ZJ, Pilhofer M, Hatzenpichler R (2024 Aug). Cultivation and visualization of a methanogen of the phylum Thermoproteota. Nature, 632(8027), 1118-1123. doi: 10.1038/s41586-024-07631-6. ID: 39048824.

6.) Lyon K, Bansil R, Bimczok D (2024 Jul 5). Profiling Luminal pH in Three-Dimensional Gastrointestinal Organoids Using Microelectrodes. Journal of visualized experiments : JoVE, (209), . doi: 10.3791/66900. ID: 39037269.

7.) Schaible GA, Jay ZJ, Cliff J, Schulz F, Gauvin C, Goudeau D, Malmstrom RR, Ruff SE, Edgcomb V, Hatzenpichler R (2024 Jul). Multicellular magnetotactic bacteria are genetically heterogeneous consortia with metabolically differentiated cells. PLoS biology, 22(7), e3002638. . ID: 38990824.

8.) Miller IR, Bui H, Wood JB, Fields MW, Gerlach R (2024 Jun). Understanding phycosomal dynamics to improve industrial microalgae cultivation. Trends in biotechnology, 42(6), 680-698. doi: 10.1016/j.tibtech.2023.12.003. ID: 38184438.

9.) Fredrikson JP, Brahmachary PP, June RK, Cox LM, Chang CB (2024 Jan). Pericellular Matrix Formation and Atomic Force Microscopy of Single Primary Human Chondrocytes Cultured in Alginate Microgels. Advanced biology, 8(1), e2300268. . ID: 37688354.

10.) Schaible GA, Jay ZJ, Cliff J, Schulz F, Gauvin C, Goudeau D, Malmstrom RR, Emil Ruff S, Edgcomb V, Hatzenpichler R (2023 Nov 27). Multicellular magnetotactic bacterial consortia are metabolically differentiated and not clonal. bioRxiv : the preprint server for biology, (), . . ID: 38076927.

Description:

The Bioimaging and Analytical Core Labs offer cutting edge imaging and analysis of intact biofilms for academia and industry at the heart of the Center for Biofilm Engineering at Montana State University. Our imaging technology allows us to capture with ultimate precision the position, interactions, activity, and identification of microbes in real-time from intact samples. With our broad range of analytical capabilities, we can determine how microbes are interacting and altering their environmental conditions. We provide one-on-one training, method development, proposal writing, troubleshooting and data analysis services to help you meet your biofilm-related analytical and imaging needs. Our staff are highly trained and specialized experts with Ph.D.’s in biofilm science. Our bioimaging and analytical and core labs are equipped with state-of-the-art technologies and methods to provide you with the best results and images of your biofilm or other complex samples.