We also thank the Keck MS & Proteomics Resource at the Yale School of Medicine for providing the nec
Instrumentation:
Thermo Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer
Q Exactive Plus Hybrid Quadrupole-Orbitrap Mass Spectrometer has increased performance and new options that enhance applications from confident DMPK qual/quan screening studies to characterization of intact monoclonal antibodies. [Product Link]
Thermo Scientific Orbitrap Fusion Tribrid Mass Spectrometer
Combines quadrupole, ion trap, and Orbitrap mass analysis into Tribrid architecture to provide depth of analysis. Enables analyzing of low-abundance, high-complexity samples to identify compounds and to quantify accurately and elucidate structures thoroughly. [Product Link]
Thermo Scientific Q Exactive HF-X Hybrid Quadrupole-Orbitrap Mass Spectrometer
HFX is our newest addition to the proteomics resource. It offers the fastest scanning rate of our Orbitraps, which improves proteomic depth for discovery applications, and integrates well with targeted applications such as parallel reaction monitoring. [Product Link]
The Keck Mass Spectrometry (MS) & Proteomics Resource at the Yale School of Medicine provides efficient and cost-effective proteomics and small molecule mass spectrometry-based services. Beside from our developed Standard Operating Procedure (SOP) offered for many of our MS services, we also strive to continue to bring state-of-the-art mass spectrometry-based biotechnologies through input and request from our users. These technologies are developed and implemented with a broad spectrum of mass spectrometry-based techniques and protein/peptide/small molecule chemistries to separate, characterize, profile, and quantify analytes from complex biological samples.