Douglas Mental Health University Institute
6875 LaSalle Boulevard
Montreal, QC H4H 1R3
https://www.douglasbrainbank.ca
RRID: RRID:SCR_025991
1.) Nishioka M, Sakashita-Kubota M, Iijima K, Hasegawa Y, Ishiwata M, Takase K, Ichikawa R, Mechawar N, Turecki G, Kato T (2026 Jan 7). Disturbances of paraventricular thalamic nucleus neurons in bipolar disorder revealed by single-nucleus analysis. Nature communications, 17(1), 1338. . PMCID: 12873406.
2.) Yang AJT, Mohammad A, Crozier RWE, Maddalena L, Tsiani E, MacNeil AJ, Spencer GE, Necakov A, Duarte-Guterman P, Stuart J, MacPherson REK (2025 Oct). Differences in inflammatory markers, mitochondrial function, and synaptic proteins in male and female Alzheimer's disease post mortem brains. Alzheimer's & dementia : the journal of the Alzheimer's Association, 21(10), e70645. . PMID: 41031399.
3.) Chawla A, Cakmakci D, Fiori LM, Zang W, Maitra M, Yang J, Żurawek D, Frosi G, Rahimian R, Mitsuhashi H, Davoli MA, Denniston R, Chen GG, Yerko V, Mash D, Girdhar K, Akbarian S, Mechawar N, Suderman M, Li Y, Nagy C, Turecki G (2025 Aug). Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression. Nature genetics, 57(8), 1890-1904. doi: 10.1038/s41588-025-02249-4. PMID: 40764843.
Based at the Douglas Research Centre, the Douglas-Bell Canada Brain Bank (DBCBB) houses a large collection of brains from people with diverse psychiatric disorders, including schizophrenia, major depression, bipolar disorder and substance use disorders, as well as brains from individuals with various neurological and developmental disorders such as amyotrophic lateral sclerosis (ALS), Alzheimer’s disease and autism spectrum disorder (ASD). In addition, the DBCBB manages a large relational database containing demographic, clinical and developmental histories from donors.
