University of California, Berkeley

Contact Info:

Rob Maxwell

https://qb3.berkeley.edu/facility/pmsl/

Grants and Identifiers:

RRID: RRID:SCR_025852

Instrumentation:

Services Provided:

Relevant Publications:

1.) Patel KM, Seed KD (2025 Aug 28). A DNA nicking Class 1 OLD family nuclease mediates phage defense in Vibrio cholerae and is countered by a phage-encoded inhibitor Nucleic Acids Research, 53(16), gkaf728. . PMCID: 12392090.

2.) Williams JK, Ngo JM, Murugupandiyan A, Croall DE, Hartzell HC, Schekman R (2025 May 16). Calpains orchestrate secretion of annexin-containing microvesicles during membrane repair The Journal of Cell Biology, 224(7), e202408159. . PMCID: 12083247.

3.) Ng HY, Whelpley DH, Adly AN, Maxwell RA, Morgan DO (2025 Apr 2). Phosphate-binding pocket on cyclin B governs CDK substrate phosphorylation and mitotic timing bioRxiv, (), 2024.02.28.582599. . PMCID: 10925351.

4.) Patel KM, Seed KD (2025 Jan 6). A Class 1 OLD family nuclease encoded by Vibrio cholerae is countered by a vibriophage-encoded direct inhibitor bioRxiv, (), 2025.01.06.631583. . PMCID: 11741312.

5.) Oh EJ, Park JI, Lee JE, Myung CH, Kim SY, Chang SE, Hwang JS (2016 Apr 12). A Novel Role of Serotonin Receptor 2B Agonist as an Anti-Melanogenesis Agent. International journal of molecular sciences, 17(4), 546. . PMID: 27077852.

6.) Lorenzini A, Fink LS, Stamato T, Torres C, Sell C (2011 Dec). Relationship of spindle assembly checkpoint fidelity to species body mass, lifespan, and developmental rate. Aging, 3(12), 1206-12. . PMID: 22201071.

Description:

Core provides multidimensional LC-MS/MS analysis including Protein ID, Proteomics Profiling, Targeted Proteomics and Post Translational Modification analysis. Quantitative proteomic services are provided using label free quantitative proteomic (LFQ) profiling, Tandem mass tagging (TMT) or SILAC approaches. Provides support for macromolecular complexes using Nano ESI.