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Peter MacCallum Cancer Centre Genotyping Core Facility

Peter MacCallum Cancer Centre

Contact Info:

Jade Cooke

305 Grattan Street

Melbourne 3000

https://www.petermac.org/research/research-technologies/genotyping-core

Grants and Identifiers:

RRID: RRID:SCR_025622

Instrumentation:

Services Provided:

Cell Line Authentication

Genotyping

Mycoplasma Testing

Relevant Publications:

1.) Lai J, Chan CW, Armitage JD, Audsley KM, Huang YK, Derrick EB, Carstensen LS, Scheffler CM, Jones ME, Sek K, Principe N, Kim JS, House IG, Chen AXY, Yap KM, Middelburg J, Munoz I, Nguyen D, Tong J, Hoang TX, Todd KL, Evrard M, Chee J, Mackay LK, Forrest ARR, Parish IA, Bosco A, Waithman J, Beavis PA, Darcy PK (2026 Mar). Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8(+) T cells in lymph nodes. Nature immunology, 27(3), 530-542. . PMCID: 12956571.


2.) de Menezes MN, Chen AXY, Kulkarni N, Sampurno S, Saw NYL, Yap KM, Pérez-Núñez I, Roth S, Deguit CDT, Haugen B, Ramsbottom KM, Munoz I, Beavis PA, Parish IA (2026 Feb 17). High efficiency CRISPR knock-in demonstrates that TCF1 is insufficient to reverse T cell exhaustion. Nature communications, 17(1), . . PMCID: 13022480.


3.) Chen AXY, Yap KM, Kim JS, Sek K, Huang YK, Dunbar PA, Wiebking V, Armitage JD, Munoz I, Todd KL, Derrick EB, Nguyen D, Tong J, Chan CW, Hoang TX, Audsley KM, van Elsas MJ, Middelburg J, Lee JN, de Menezes MN, Cole TJ, Li J, Scheffler C, Scott AM, Mackay LK, Waithman J, Oliaro J, Harrison SJ, Parish IA, Lai J, Porteus MH, House IG, Darcy PK, Beavis PA (2025 Aug). Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery. Nature, 644(8075), 241-251. . PMCID: 12328239.


Description:

Provides mouse genotyping service, from extraction of genomic DNA from tissue to reporting of genotypes. Offers Mycoplasma testing of any cell line and authentication of human cell lines.