Beth Israel Deaconess Medical Center
Towia Libermann
99 Brookline Ave.
Research North Building
Boston, MA 02115
https://www.bidmc.org/research/core-facilities/genomics-proteomics-corehttps://www.bidmc.org/research/core-facilities/genomics-proteomics-core
RRID: RRID:SCR_025689
Agilent SureScan Dx Microarray Scanner
SureScan Dx microarray scanner system analyzes many genomics and cytogenetics microarrays. [Product Link]
RRID:SCR_019544
BioTechne Ella
Fully automized multiplex immunoassays
Tecan Tecan Fluent 780
liquid handling robot
Computational - Bioinformatics
Computational - Biostatistics
Consultation
Cytokine Assays
Data Analysis
Data Analysis And Interpretation
Data Visualization
Discovery Science
ELISA
Immunoassay
Pathway Interpretation
Proteomics
Proteomics Analysis
Sample Preparation
SomaScan Proteomics
1.) Sasamoto N, Ngo L, Vitonis AF, Dillon ST, Prasad P, Laufer MR, As-Sanie S, Schrepf A, Missmer SA, Libermann TA, Terry KL (2024 Aug). Plasma proteins and persistent postsurgical pelvic pain among adolescents and young adults with endometriosis. American journal of obstetrics and gynecology, 231(2), 240.e1-240.e11. doi: 10.1016/j.ajog.2024.03.005. ID: 38462144.
2.) Zhang X, Zhao L, Ngo LH, Dillon ST, Gu X, Lai M, Simon TG, Chan AT, Giovannucci EL, Libermann TA, Zhang X (2024 Aug 1). Prediagnostic plasma proteomics profile for hepatocellular carcinoma. Journal of the National Cancer Institute, 116(8), 1343-1355. . ID: 38688524.
3.) Zhao L, Zhang X, Birmann BM, Danford CJ, Lai M, Simon TG, Chan AT, Giovannucci EL, Ngo L, Libermann TA, Zhang X (2024 Jun 11). Pre-diagnostic plasma inflammatory proteins and risk of hepatocellular carcinoma in three population-based cohort studies from the United States and the United Kingdom. International journal of cancer, (), . doi: 10.1002/ijc.35054. ID: 38861327.
4.) Winter RW, Muftah M, Gu X, Dillon ST, Libermann TA, Chan WW (2024 May 28). Comparative Assessment of Esophageal Proteomics in Eosinophilic Esophagitis Using SOMAscan. Gastroenterology, (), . pii: S0016-5085(24)04999-0. doi: 10.1053/j.gastro.2024.05.022. ID: 38815709.
5.) Diakos NA, Swain L, Bhave S, Qiao X, Libermann T, Haywood J, Goel S, Annamalai S, Esposito M, Chweich H, Faugno A, Kapur NK (2024 Feb 26). Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock. Journal of cardiovascular translational research, (), . doi: 10.1007/s12265-024-10501-1. ID: 38409476.
6.) Courtney Y, Head JP, Yimer ED, Dani N, Shipley FB, Libermann TA, Lehtinen MK (2024 Jan 16). A choroid plexus apocrine secretion mechanism shapes CSF proteome and embryonic brain development. bioRxiv : the preprint server for biology, (), . . ID: 38260341.
7.) Gonçalves M, Khera T, Otu HH, Narayanan S, Dillon ST, Shanker A, Gu X, Jung Y, Ngo LH, Marcantonio ER, Libermann TA, Subramaniam B (2023 Oct 13). Multivariable model of postoperative delirium in cardiac surgery patients: proteomic and demographic contributions. medRxiv : the preprint server for health sciences, (), . . ID: 37333093.
8.) Dillon ST, Vasunilashorn SM, Otu HH, Ngo L, Fong T, Gu X, Cavallari M, Touroutoglou A, Shafi M, Inouye SK, Xie Z, Marcantonio ER, Libermann TA (2023 Sep 15). Aptamer-Based Proteomics Measuring Preoperative Cerebrospinal Fluid Protein Alterations Associated with Postoperative Delirium. Biomolecules, 13(9), . . ID: 37759795.
9.) Accortt E, Mirocha J, Zhang D, Kilpatrick SJ, Libermann T, Karumanchi SA (2023 Aug). Perinatal mood and anxiety disorders: biomarker discovery using plasma proteomics. American journal of obstetrics and gynecology, 229(2), 166.e1-166.e16. doi: 10.1016/j.ajog.2023.01.012. ID: 36649818.
10.) Sasamoto N, Ngo L, Vitonis AF, Dillon ST, Sieberg CB, Missmer SA, Libermann TA, Terry KL (2023 Aug 1). Plasma proteomic profiles of pain subtypes in adolescents and young adults with endometriosis. Human reproduction (Oxford, England), 38(8), 1509-1519. . ID: 37196326.
11.) Blatt S, Kämmerer PW, Krüger M, Surabattula R, Thiem DGE, Dillon ST, Al-Nawas B, Libermann TA, Schuppan D (2023 Mar 30). High-Multiplex Aptamer-Based Serum Proteomics to Identify Candidate Serum Biomarkers of Oral Squamous Cell Carcinoma. Cancers, 15(7), . . ID: 37046731.
12.) Vasunilashorn SM, Dillon ST, Marcantonio ER, Libermann TA (2023). Application of Multiple Omics to Understand Postoperative Delirium Pathophysiology in Humans. Gerontology, 69(12), 1369-1384. . ID: 37722373.
13.) Piera-Velazquez S, Dillon ST, Gu X, Libermann TA, Jimenez SA (2022). Aptamer proteomics of serum exosomes from patients with Primary Raynaud PloS one, 17(12), e0279461. . ID: 36548367.
The Center provides investigators access to comprehensive interdisciplinary, translational, and clinically-oriented facilities for high-sensitivity and high-throughput proteomics services. The Center has over 20 years of experience in precision medicine and proteomics biomarker discovery in tissue and biological fluids. We are the only service provider in the Boston are for the exciting and most comprehensive, highly multiplex 11,000-protein SomaScan v5.0 assay. We provide assistance in study design, experimental execution, data analysis, and systems biology, while also serving as a forum for education, scientific interactions, and cross-fertilization in proteomics.
