Peter MacCallum Cancer Centre

Contact Info:

Kaylene Simpson

https://www.petermac.org/research/research-technologies/victorian-centre-functional-genomics-vcfg

Grants and Identifiers:

RRID: RRID:SCR_025582

Instrumentation:

Services Provided:

Relevant Publications:

1.) Zhang X, Xu R, Zorin D, Pappas EG, Tang J, Bai Y, Qin VM, von Scheidt B, Huang R, Kulakowska W, Darido C, Darcy PK, Kershaw MH, Slaney CY (2025 Aug 21). Optimised modular anti‐FLAG CAR T cells for solid tumor therapy Clinical & Translational Immunology, 14(8), e70046. . PMCID: 12370372.

2.) Buco PA, Tandazo-Castillo W, Chalk AM, Pilcher C, Holien JK, Heierhorst J, Tan TY, Koren A, Smeets MF, Walkley CR (2025 Jul 21). Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication bioRxiv, (), 2025.07.21.666025. . PMCID: 12330659.

3.) Pishas KI, Cowley KJ, Llaurado-Fernandez M, Kim H, Luu J, Vary R, Bowden NA, Campbell IG, Carey MS, Simpson KJ, Cheasley D (2024 Sep 19). High-throughput drug screening identifies novel therapeutics for Low Grade Serous Ovarian Carcinoma Scientific Data, 11(), 1024. . PMCID: 11413243.

Description:

Core to perform novel discovery-based high throughput compound, CRISPR and RNAi screens at any scale in both 2D and 3D formats, using liquid handling instruments, automated high content imaging microscopes, live imaging systems and large reagent libraries.