University of Notre Dame
Contact Info:
Melissa Stephens
019 Galvin Life Science
Notre Dame, IN 46556
Grants and Identifiers:
RRID: RRID:SCR_025555
Instrumentation:
2100 Bioanalyzer Instrument
The 2100 Bioanalyzer system is an automated electrophoresis tool that provides precise analytical evaluation of various samples types in many workflows, including next generation sequencing (NGS), gene expression, biopharmaceutical, and gene editing research. Digital data is provided in a timely manner and delivers objective assessment of sizing, quantitation, integrity and purity from DNA, RNA, and proteins. Minimal sample volumes are required for an accurate result, and the data may be exported in a many different formats for ease-of-use. [Product Link]
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Agilent 4150 TapeStation System
This TapeStation System analyzes nucleic acids for up to 16 samples per run. [Product Link]
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Illumina MiSeq System
Access focused applications such as targeted resequencing, metagenomics, small genome sequencing, targeted gene expression profiling, and more. MiSeq reagents enable up to 15 Gb of output with 25 million sequencing reads and 2 × 300 bp read lengths. [Product Link]
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Illumina NextSeq 1000 and NextSeq 2000 Sequencing Systems
Benchtop sequencers that allow you to explore new science across variety of current and emerging applications, with higher efficiency and fewer restraints. [Product Link]
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Services Provided:
10x Genomics Xenium Spatial Transcriptomics
ABI3730XL Sanger Sequencing And Fragment Analysis
BluePippin Automated Size Selection
Custom And Specialty NGS Workflows
High-intensity Acoustic Shearing
Illumina RNA/DNA NGS Library Construction
Visium HD Spatial Transcriptomics
Relevant Publications:
Description:
The Genomics & Bioinformatics Core Facility (GBCF) at Notre Dame serves a diverse research community that spans basic biomedical research in human disease, vector disease research, population genomics, and environmental genomics. Utilizing Illumina sequencing, single-cell analysis, and spatial transcriptome analysis, we offer comprehensive solutions designed to acquire data for a broad range of applications including metagenomics, cancer genomics, microbial genomics, transcriptomics, and epigenomics for both model and non-model systems. Applying robust bioinformatics tools and biocomputing resources, we offer guidance and analysis workflows specifically tailored to your needs.
