Emory University
Contact Info:
Frank Harris
2015 Uppergate Drive
Atlanta, GA 30322
https://www.pedsresearch.org/research/cores/biomarkers-core
Grants and Identifiers:
RRID: RRID:SCR_025574
Instrumentation:
Thermo Scientific ISQ 7000 Single Quadrupole GC-MS System
Thermo Scientific ISQ 7000 is a Single Quadrupole GC-MS system offers extended uptime and robustness to maximize sample throughput, along with routine easy-to-use smart tools to simplify operation and speed up instrument familiarization. Featuring a range of configurations at different level of performances, the ISQ 7000 GC-MS is a flexible fit-for-purpose platform, fully upgradable from base to advanced highly sensitive configuration to boost performance when needed and ready-to-fit with continuous changing in regulations. [Product Link]
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Thermo Scientific Q Exactive HF Orbitrap LC-MS/MS System
Thermo Exactive benchtop Orbitrap operates with a Waters Acquity UPLC and generates high resolution, high mass accuracy full Mass Spectrometry data. [Product Link]
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Waters 2695 HPLC System
High performance liquid chromatographic system with quaternary, low pressure mixing pump and inline vacuum degassing. It has wavelengths of 190 to 800 nm and flow rates from 50 uL per min to 5 mL per min. It has temperature control from 4 to 40 C. [Product Link]
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Thermo Scientific Orbitrap Exploris 120
High-resolution, accurate-mass (HRAM) mass spectrometer designed for qualitative and quantitative analysis
Thermo Scientific TSQ Quantis Liquid Chromatograph Mass Spectrometer
Ultra High Performance Liquid Chromatograph/Triple Quadrupole Mass Spectrometer (UHPLC-MS/MS)
Services Provided:
Quantitative Targeted Analysis For Selected Metabolites
Targeted Small Molecule Quantitation (MRM)
Relevant Publications:
Description:
The Pediatric Metabolomics and Biomarkers Core provides innovative approaches to accomplish unbiased, highly sensitive, and biologically meaningful evaluation of metabolites and metabolic pathways in a wide range of sample types. Techniques offered include high-resolution and polytargeted metabolomics, isotope tracing and fluxomics, fully quantitative targeted analysis, and metabolomic imaging. Unique to Emory's facilities, the core supports hypothesis-driven research to investigate specific biomarkers of interest and corresponding metabolomic pathways, thus supporting research in disease diagnostics, drug development, and personalized medicine.
