Harvard University
401 Park Drive, 3rd Floor east
Boston, MA 02215
https://bioinformatics.sph.harvard.edu/
RRID: RRID:SCR_025373
Bioinformatics Analysis
Bioinformatics Grant Proposal Support
Bioinformatics Project Planning
Bioinformatics Training
Computational - Bioinformatics
Consulting
Custom And Specialty NGS Workflows
RNA-Seq Training
Spatial / Single Cell Training
1.) Jachim SK, Venkatasubramanian D, Senevirathne G, Zhu AS, Vitale CS, Melendez DL, Zhang CH, Lassar AB, Capellini TD, Craft AM (2026 Jan 9). Leveraging single cell multiomic analyses to identify gene regulatory networks that drive human articular cartilage cell fate. Osteoarthritis and cartilage, (), . . PMCID: 12910476.
2.) Sullivan ZA, Wong BJ, Kapoor V, Vincze PK, Kaplan HS, Giraudet P, Watson BR, Misherghi A, Lourido S, Moffitt JR, Dulac C (2025 Dec 8). Brain-immune interactions generate pathogen-specific sickness states bioRxiv, (), 2025.12.06.692770. . PMCID: 12713759.
3.) Pignatti E, Jiang L, Shah MS, Karpurapu A, Miao J, Liu Y, Berber M, Kalagara R, Butler AE, Skalnik DG, Rosen V, Breault DT, Carlone DL (2025 Dec). CXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development. Developmental biology, 528(), 204-215. . PMID: 40915528.
4.) Iuchi S, Paulo JA (2025 Feb 25). The role of MKI67 in the regulation of 60S pre-ribosome nucleolar export, transcripts, energy supply, and apoptosis bioRxiv, (), 2025.02.13.638155. . PMCID: 11844515.
We analyse all types of high-throughput sequencing data from RNA-seq and single cell RNA-seq to variant sequencing (exome or whole genome), to ChIP-seq or bisulfite sequencing. With spatial profiling methods becoming more accessible, we have developed new workflows for spatial transcriptomic analysis and multimodal integration. We offer a dedicated bioinformatics training program for researchers interested in learning basic data skills and the analysis of high-throughput sequencing data. Our workshops focus on utilizing best practices in the field and research reproducibility.
