Harvard University

Contact Info:

401 Park Drive, 3rd Floor east

Boston, MA 02215

https://bioinformatics.sph.harvard.edu/

Grants and Identifiers:

RRID: RRID:SCR_025373

Instrumentation:

Services Provided:

Bioinformatics Analysis

Bioinformatics Grant Proposal Support

Bioinformatics Project Planning

Bioinformatics Training

Computational - Bioinformatics

Consulting

Custom And Specialty NGS Workflows

RNA-Seq Training

Spatial / Single Cell Training

Relevant Publications:

1.) Pignatti E, Jiang L, Shah MS, Karpurapu A, Miao J, Liu Y, Berber M, Kalagara R, Butler AE, Skalnik DG, Rosen V, Breault DT, Carlone DL (2025 Dec). CXXC Finger Protein 1 drives BMP signaling and progenitor cell differentiation during limb development. Developmental biology, 528(), 204-215. . PMID: 40915528.

2.) Iuchi S, Paulo JA (2025 Feb 25). The role of MKI67 in the regulation of 60S pre-ribosome nucleolar export, transcripts, energy supply, and apoptosis bioRxiv, (), 2025.02.13.638155. . PMCID: 11844515.

Description:

We analyse all types of high-throughput sequencing data from RNA-seq and single cell RNA-seq to variant sequencing (exome or whole genome), to ChIP-seq or bisulfite sequencing. With spatial profiling methods becoming more accessible, we have developed new workflows for spatial transcriptomic analysis and multimodal integration. We offer a dedicated bioinformatics training program for researchers interested in learning basic data skills and the analysis of high-throughput sequencing data. Our workshops focus on utilizing best practices in the field and research reproducibility.